1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. PARP
  4. PARP Isoform



PARP Related Products (66):

Cat. No. Product Name Effect Purity
  • HY-13688A
    Inhibitor 98.01%
    PJ34 is a potent specific inhibitor of PARPl/2 with IC50 of 110 nM and 86 nM, respectively.
  • HY-104044
    Inhibitor 99.97%
    Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor, with IC50 values of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively.
  • HY-N0674
    Inhibitor 99.77%
    Dehydrocorydaline (13-Methylpalmatine) is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP.
  • HY-13688
    PJ34 hydrochloride
    Inhibitor 99.10%
    PJ34 hydrochloride is an inhibitor of PARP1/2 with IC50 of 110 nM and 86 nM, respectively.
  • HY-145471
    Inhibitor 99.94%
    KSQ-4279 (USP1-IN-1, Formula I) is a USP1 and PARP inhibitor (extracted from patent WO2021163530).
  • HY-12022
    Inhibitor 99.92%
    3-Aminobenzamide (PARP-IN-1) is a potent inhibitor of PARP with IC50 of appr 50 nM in CHO cells, and acts as a mediator of oxidant-induced myocyte dysfunction during reperfusion.
  • HY-108413
    Talazoparib tosylate
    Inhibitor 99.72%
    Talazoparib tosylate (BMN 673ts) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1.
  • HY-108631
    EB-47 dihydrochloride
    Inhibitor 99.72%
    EB-47 dihydrochloride, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.
  • HY-13968
    JW 55
    Inhibitor 99.94%
    JW 55 is a potent and selective β-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2).
  • HY-12975
    Inhibitor 99.65%
    AZ6102 is a potent dual TNKS1 and TNKS2 inhibitor, with IC50s of 3 nM and 1 nM, respectively, and alao has 100-fold selectivity against other PARP family enzymes, with IC50s of 2.0 μM, 0.5 μM, and >3 μM, for PARP1, PARP2, and PARP6, respectively.
  • HY-137450
    Inhibitor 99.44%
    Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor.
  • HY-130644
    Inhibitor 99.82%
    iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.
  • HY-100828
    Inhibitor ≥98.0%
    BGP-15 is a PARP inhibitor, with an IC50 and a Ki of 120 and 57 μM, respectively.
  • HY-119653
    Inhibitor 98.17%
    AZ9482 is a triple PARP1/2/6 inhibitor, with IC50 values of 1 nM, 1 nM and 640 nM for PARP1, PARP2 and PARP6, respectively.
  • HY-15045
    Inhibitor 98.19%
    INO-1001 is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor.
  • HY-W016412
    Coenzyme Q0
    Inhibitor ≥99.0%
    Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound can be derived from Antrodia cinnamomea.
  • HY-100862
    Inhibitor 98.39%
    BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions.
  • HY-114869
    Inhibitor ≥99.0%
    DPQ is a potent PARP-1 inhibitor.
  • HY-N6818
    Activator 99.78%
    5,7,4'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) that is a famous medicinal plant from Thailand.
  • HY-15044
    Inhibitor ≥98.0%
    NU1025 is a potent PARP inhibitor with an IC50 of 400 nM and a Ki of 48 nM.