1. Cell Cycle/DNA Damage
    Epigenetics
  2. PARP
  3. BRCA1-IN-2

BRCA1-IN-2 

Cat. No.: HY-100862
Handling Instructions

BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions.

For research use only. We do not sell to patients.

BRCA1-IN-2 Chemical Structure

BRCA1-IN-2 Chemical Structure

CAS No. : 1622262-55-8

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Description

BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions[1].

IC50 & Target

IC50: 0.31 μM (BRCA1)[1]
Kd: 0.3 μM (BRCA1)[1]

Molecular Weight

544.54

Formula

C₂₆H₃₃N₄O₇P

CAS No.

1622262-55-8

SMILES

O=C(N[[email protected]@H](COP(O)(O)=O)C(NCC(NCCCCC1=CC=CC=C1)=O)=O)CCC2=CNC3=C2C=CC=C3

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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BRCA1-IN-2
Cat. No.:
HY-100862
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