1622262-55-8
1622262-55-8
Chemical Structure
BRCA1-IN-2
- CAS No.: 1622262-55-8
- Formula:C26H33N4O7P
- Molecular Weight:544.54
IUPAC Name: (S)-2-(3-(1H-indol-3-yl)propanamido)-3-oxo-3-((2-oxo-2-((4-phenylbutyl)amino)ethyl)amino)propyl dihydrogen phosphate
InChIKey: TYEYIJQDNULZJQ-QHCPKHFHSA-N
SMILES: O=C(N[C@@H](COP(O)(O)=O)C(NCC(NCCCCC1=CC=CC=C1)=O)=O)CCC2=CNC3=C2C=CC=C3
Biological Activity: BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BRCA1-IN-2 | 98.12% | BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
BRCA1-IN-2 (Standard) | ≥98% | BRCA1-IN-2 (Standard) is the analytical standard of BRCA1-IN-2 (HY-100862). This product is intended for research and analytical applications. BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
