Copy Link Print Information

Dehydrocorydaline

(Synonyms: 13-Methylpalmatine)
47 Cited Publications
Customer Review

Based on 47 publication(s) in Google Scholar

Dehydrocorydaline (13-Methylpalmatine) is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.

For research use only. We do not sell to patients.

  • Purity: 98.42%
  • CAS No.: 30045-16-0
  • Formula: C22H24NO4+
  • Molecular Weight:366.43
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Dehydrocorydaline Chemical Structure
    Dehydrocorydaline Chemical Structure
  • Experimental Validation Results for Dehydrocorydaline
  • Experimental Validation Results for Dehydrocorydaline
  • Experimental Validation Results for Dehydrocorydaline
  • Experimental Validation Results for Dehydrocorydaline
  • Experimental Validation Results for Dehydrocorydaline
  • Experimental Validation Results for Dehydrocorydaline
  • Experimental Validation Results for Dehydrocorydaline
CAS No.: 30045-16-0
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Dehydrocorydaline:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Solvent & Solubility
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Dehydrocorydaline

More
Customer Validation & Images
Histological Imaging/StainingRT-PCRIFCell Proliferation/Viability AssayWB
  • Histological Imaging/Staining
  • RT-PCR
  • WB
  • IF
  • Cell Proliferation/Viability Assay
  • WB
  • WB

All Bcl-2 Family Isoforms

More

All Caspase Isoforms

More

All PARP Isoforms

More

All p38 MAPK Isoforms

More

All Parasite Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Dehydrocorydaline Chemical Structure
    Dehydrocorydaline Chemical Structure
    1/16
  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 Apr 12;26(1):136. [Abstract]

    Customer Validation
     Images of mice lung tissue slices stained with H&E, Masson, and Sirius Red treated with L-DHC (Dehydrocorydaline) 5 mg/kg, H-DHC: 10 mg/kg.

  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 Apr 12;26(1):136. [Abstract]

    Customer Validation
     RT-qPCR results for Col1a1 and Fn1 expression levels of mice lung tissue treated with L-DHC (Dehydrocorydaline) 5 mg/kg, H-DHC: 10 mg/kg.

  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 Apr 12;26(1):136. [Abstract]

    Customer Validation
     Collagen 1 and Fibronectin of mice lung tissues are analyzed using Western blot treated with L-DHC (Dehydrocorydaline) 5 mg/kg, H-DHC: 10 mg/kg.

  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 Apr 12;26(1):136. [Abstract]

    Customer Validation
     Immunofluorescence images of α-SMA, Collagen 1, and Fibronectin in mice lung tissue slices treated with L-DHC (Dehydrocorydaline) 5 mg/kg, H-DHC: 10 mg/kg.

  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 Apr 12;26(1):136. [Abstract]

    Customer Validation
     CCK8 assay to determine the impact of Dehydrocorydaline (DHC) (5, 10, 30, 50, 80, 100, 150 μM) on HPFs viability.

  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2018 May 23;499(4):743-750. [Abstract]

    Customer Validation
     Astrocytes are cultured with p38 and JNK activator of DHC and ANS, respectively, at the indicated concentrations for 24 h. Then, all cells are harvested for western blot analysis of p-p38 and p-JNK. Astrocytes are pretreated with DHC (500 nM) or ANS (10 mM) for 24 h, followed by Fru (5 mM) for an additional 24 h.

  • 1/16

    Dehydrocorydaline purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2018 Sep 5;503(2):467-473. [Abstract]

    Customer Validation
     The increase of Bcl-2 and decrease of Bax, cleaved Caspase-3 and PARP induced by Ulk1- inhibition in LPS-exposed AST are abrogated by the Dehydrocorydaline chloride (DHC) or Anisomycin (ANS) pre-treatment

  • Dehydrocorydaline