1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. PARP
  4. TNKS1/PARP5A Inhibitors

TNKS1/PARP5A Inhibitors

PARP

PARP1

PARP2

PARP3

PARP4

TNKS1/PARP5A

TNKS2/PARP5B

PARP10

PARP14

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform TNKS1/PARP5A together.

Please try each isoform separately.

TNKS1/PARP5A Specific Inhibitors
Product Name TNKS1/PARP5A PARP1 PARP2 PARP3 PARP4 TNKS2/PARP5B PARP10 TNKS1/PARP5A Selectivity Purity
MN-64
TNKS1, IC50: 6 nM
ARTD1, IC50: 19.1 μM
ARTD2, IC50: 39.4 μM
   
TNKS2, IC50: 72 nM
  Selective Inhibitor 98.22%
Olaparib
tankyrase-1, IC50: 1.5 μM
PARP-1, IC50: 5 nM
PARP-2, IC50: 1 nM
        Pan Inhibitor 99.98%
XAV-939
TNKS1, IC50: 5 nM
ARTD1, IC50: 5500 nM
ARTD2, IC50: 479 nM
   
TNKS2, IC50: 2 nM
  Pan Inhibitor 98.04%
Niraparib
TANK-1, IC50: 570 nM
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
    Pan Inhibitor 99.93%
RK-287107
tankyrase-1, IC50: 14.3 nM
       
tankyrase-2, IC50: 10.6 nM
  Pan Inhibitor
Niraparib tosylate
TANK-1, IC50: 570 nM
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
    Pan Inhibitor 99.52%
G007-LK
TNKS1, IC50: 46 nM
       
TNKS2, IC50: 25 nM
  Pan Inhibitor 99.24%
ME0328
ARTD5/TNKS1, IC50: 47.3 μM
ARTD1/PARP1, IC50: 6.3 μM
ARTD2/PARP2, IC50: 10.8 μM
ARTD3/PARP3, IC50: 0.89 μM
 
ARTD6/TNKS2, IC50: 34.3 μM
ARTD10/PARP10, IC50: 71.3 μM
Pan Inhibitor 99.34%
Niraparib hydrochloride
TANK-1, IC50: 570 nM
PARP-1, IC50: 3.8 nM
PARP-2, IC50: 2.1 nM
PARP-3, IC50: 1300 nM
V-PARP, IC50: 330 nM
    Pan Inhibitor 99.80%
K-756
TNKS1, IC50: 31 nM
       
TNKS2, IC50: 36 nM
  Pan Inhibitor >99.0%