TNKS1/PARP5A

TNKS1/PARP5A Related Products (24):

By Type:	Pan (23) Selective (1)

Cat. No.	Product Name	Effect	Purity

HY-10162

Olaparib	Inhibitor	99.98%
Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC₅₀s of 5 and 1 nM for PARP1 and PARP2, respectively.

HY-15147

XAV-939	Inhibitor	99.91%
XAV-939 is a Tankyrase inhibitor.

HY-10619

Niraparib	Inhibitor	99.96%
Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC₅₀s of 3.8 and 2.1 nM, respectively.

HY-10619B

Niraparib tosylate	Inhibitor	99.97%
Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC₅₀ of 3.8 and 2.1 nM, respectively.

HY-12438

G007-LK	Inhibitor	99.42%
G007-LK is a potent and selective inhibitor of TNKS1 and TNKS2, with IC₅₀s of 46 nM and 25 nM, respectively.

HY-148566

OUL232	Inhibitor
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15.

HY-152198

Tankyrase-IN-4	Inhibitor
Tankyrase-IN-4 is a tankyrase 1 (TNKS1) inhibitor with an IC₅₀ value of 0.8 nM.

HY-152197

Tankyrase-IN-3	Inhibitor
Tankyrase-IN-3 is a tankyrase 1 (TNKS1) inhibitor with an IC₅₀ value of 22 nM.

HY-10619A

Niraparib hydrochloride	Inhibitor	99.76%
Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC₅₀s of 3.8 and 2.1 nM, respectively.

HY-100225

ME0328	Inhibitor	99.87%
ME0328 is a potent and selective ARTD3/PARP3 inhibitor with an IC₅₀ of 0.89±0.28 μM.

HY-122661

Mefuparib hydrochloride	Inhibitor	98.94%
Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC₅₀s of 3.2 nM and 1.9 nM, respectively.

HY-12418

Stenoparib	Inhibitor	≥98.0%
E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC₅₀s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using ³²P-NAD⁺ as substrate.

HY-123892

RK-287107	Inhibitor	99.81%
RK-287107 is a potent and specific tankyrase inhibitor with IC₅₀s of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively.

HY-19351

MN-64	Inhibitor	99.73%
MN-64 is a potent tankyrase 1 inhibitor, with IC₅₀s of 6 nM, 72 nM, 19.1 μM, and 39.4 μM for TNKS1, TNKS2, ARTD1 and ARTD2, respectively.

HY-145267

OM-153	Inhibitor	99.59%
OM-153 is a potent and orally active tankyrase inhibitor with IC₅₀s of 13 nM and 2 nM for tankyrase 1 and tankyrase 2 (TNKS1/2), respectively.

HY-U00422

K-756	Inhibitor	99.76%
K-756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC₅₀s of 31 and 36 nM, respectively.

HY-147886

PARP1-IN-11	Inhibitor	98.58%
PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC₅₀ value of 0.082 µM.

HY-10619E

Niraparib tosylate hydrate	Inhibitor
Niraparib (MK-4827) tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC₅₀s of 3.8 and 2.1 nM, respectively.

HY-145266

OM-1700	Inhibitor
OM-1700 is a potent tankyrase inhibitor with IC₅₀s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively.

HY-108516

TC-E 5001	Inhibitor
TC-E 5001 is an inhibitor of Wnt pathway that inhibits tankyrase 1/2 (TNKS1/2) via novel adenosine pocket binding, with K_ds of 79 nM and 28 nM, respectively.

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