664993-53-7
664993-53-7
Chemical Structure
JW 55
- CAS No.: 664993-53-7
- Formula:C25H26N2O5
- Molecular Weight:434.48
IUPAC Name: N-(4-(((4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamide
InChIKey: ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CO1)NC2=CC=C(C(NCC3(C4=CC=C(OC)C=C4)CCOCC3)=O)C=C2
Biological Activity: JW 55 is a potent and selective β-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). JW 55 decreases auto-PARsylation of TNKS1/2 in vitro with IC50s of 1.9 μM and 830 nM respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JW 55 | 99.83% | JW 55 is a potent and selective β-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). JW 55 decreases auto-PARsylation of TNKS1/2 in vitro with IC50s of 1.9 μM and 830 nM respectively. | ||||||||||||||||||||
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