Anti-Influenza agent 4 

Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC₅₀s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively^[1].

EC₅₀: 150±0.07 nM (A/Roma), 62±0.02 nM (A/Parma)^[1]

Anti-Influenza agent 4 (compound 5) (0-500 μM; 24 and 48 h) exhibits low cytotoxicity in MDCK cells^[1].
Anti-Influenza agent 4 shows highly antiviral activity against influenza strain A/Roma and A/Parma with EC₅₀s of 150±0.07 nM and 62±0.02 nM, respectively^[1].
Anti-Influenza agent 4 shows IC₅₀s of 244 nM and 230.7 nM against influenza strain A/Roma and A/Parma in hemolysis inhibition assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

386.42

C₁₉H₁₈N₂O₅S

522625-85-0

O=C(NC1=CC=CC(S(=O)(NCC2=CC=CO2)=O)=C1)C3=CC=C(OC)C=C3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Agamennone M, Pietrantoni A, Superti F. Identification of small molecules acting against H1N1 influenza A virus. Virology. 2016 Jan 15;488:249-58.  [Content Brief]