MA32
Based on 1 Customer Validation
MA32 is a small-molecule binder of CAPON with a Kd of 74 μM. MA32 can be used for Alzheimer’s disease research.
For research use only. We do not sell to patients.
- Purity : 98.92%
- CAS No.: 773864-68-9
- Formula: C24H20N2O5
- Molecular Weight:416.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Chemical Information
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CAS No. 773864-68-9
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Appearance Solid
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Molecular Weight 416.43
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Formula C24H20N2O5
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SMILES
O=C(C1=CC=CO1)NC2=CC=C(OC)C(NC(C3=C(OC)C=C(C=CC=C4)C4=C3)=O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (60.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4014 mL | 12.0068 mL | 24.0136 mL | 60.0341 mL |
| 5 mM | 0.4803 mL | 2.4014 mL | 4.8027 mL | 12.0068 mL | |
| 10 mM | 0.2401 mL | 1.2007 mL | 2.4014 mL | 6.0034 mL | |
| 15 mM | 0.1601 mL | 0.8005 mL | 1.6009 mL | 4.0023 mL | |
| 20 mM | 0.1201 mL | 0.6003 mL | 1.2007 mL | 3.0017 mL | |
| 25 mM | 0.0961 mL | 0.4803 mL | 0.9605 mL | 2.4014 mL | |
| 30 mM | 0.0800 mL | 0.4002 mL | 0.8005 mL | 2.0011 mL | |
| 40 mM | 0.0600 mL | 0.3002 mL | 0.6003 mL | 1.5009 mL | |
| 50 mM | 0.0480 mL | 0.2401 mL | 0.4803 mL | 1.2007 mL | |
| 60 mM | 0.0400 mL | 0.2001 mL | 0.4002 mL | 1.0006 mL |