1140964-99-3

Stenoparib Chemical Structure
1140964-99-3

Chemical Structure

Stenoparib

Synonym(s): E7449; 2X-121

  • CAS No.: 1140964-99-3
  • Formula:C18H15N5O
  • Molecular Weight:317.34

IUPAC Name: 8-(isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one

InChIKey: JLFSBHQQXIAQEC-UHFFFAOYSA-N

SMILES: O=C1NNC2=C3C1=CC=CC3=NC(CN4CC5=C(C=CC=C5)C4)=N2

Biological Activity: Stenoparib (E7449) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ～50 and ～50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.

Cat. No. Product Name Purity Description Pricing
HY-12418 		Stenoparib 98.0% Stenoparib (E7449) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ～50 and ～50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

Keywords