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Utrophin modulator 1 is a potent utrophin modulator (upregulates utrophin protein levels), with an EC50 of 0.11 μM. Utrophin modulator 1 can be used in study of duchenne muscular dystrophy (DMD).

For research use only. We do not sell to patients.

Utrophin modulator 1 Chemical Structure

Utrophin modulator 1 Chemical Structure

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Description

Utrophin modulator 1 is a potent utrophin modulator (upregulates utrophin protein levels), with an EC50 of 0.11 μM. Utrophin modulator 1 can be used in study of duchenne muscular dystrophy (DMD)[1].

In Vitro

Utrophin modulator 1 (compound 76) (0.1, 1.0, 10 μM; 24 h) upregulates utrophin protein levels in H2K-mdx cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: H2K-mdx cells
Concentration: 0.1, 1.0, 10 μM
Incubation Time: 24 h
Result: Increased utrophin protein, which up to 2.5 fold.
Molecular Weight

382.42

Formula

C22H18N6O

SMILES

O=C(NN)C1=NC(N2CC(C=CC=C3)=C3C2)=CC(C4=CC(N=CC=C5)=C5C=C4)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Utrophin modulator 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Utrophin modulator 1
Cat. No.:
HY-150077
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