Utrophin modulator 1
Utrophin modulator 1 is a potent utrophin modulator (upregulates utrophin protein levels), with an EC50 of 0.11 μM. Utrophin modulator 1 can be used in study of duchenne muscular dystrophy (DMD).
For research use only. We do not sell to patients.
- CAS No.: 3068935-32-7
- Formula: C22H18N6O
- Molecular Weight:382.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Utrophin modulator 1 (compound 76) (0.1, 1.0, 10 μM; 24 h) upregulates utrophin protein levels in H2K-mdx cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:H2K-mdx cells
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Concentration:0.1, 1.0, 10 μM
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Incubation Time:24 h
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Result:Increased utrophin protein, which up to 2.5 fold.
Chemical Information
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CAS No. 3068935-32-7
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Molecular Weight 382.42
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Formula C22H18N6O
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SMILES
O=C(NN)C1=NC(N2CC(C=CC=C3)=C3C2)=CC(C4=CC(N=CC=C5)=C5C=C4)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)