130017-40-2
130017-40-2
Chemical Structure
K-756
- No. CAS: 130017-40-2
- Formula:C24H27N5O3
- Molecular Weight:433.50
IUPAC Name: 3-((1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl)methyl)-3,4-dihydroquinazolin-2(1H)-one
InChIKey: GWXCGEJJQFHPPA-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C=CC=C2)CN1CC3CCN(C4=C5C=C(OC)C(OC)=CC5=NC=N4)CC3
Biological Activity: K-756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC50s of 31 and 36 nM, respectively.
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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K-756 | 99.25% | K-756 is a direct and selective tankyrase (TNKS) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC50s of 31 and 36 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.62
HY-161512hAChE/hBACE-1-IN-4 -
Similarity Score 0.62
HY-141831STF-1084 -
Similarity Score 0.59
HY-145070Enpp-1-IN-9 -
Similarity Score 0.59
HY-149462KN1022 -
Similarity Score 0.59
HY-112412PDGFR Tyrosine kinase-IN-1 -
Similarity Score 0.59
HY-18078PQ-10 -
Similarity Score 0.58
HY-148514CT52923 -
Similarity Score 0.57
HY-153398Enpp-1-IN-17 -
Similarity Score 0.56
HY-16639ML314 -
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