1. Cell Cycle/DNA Damage
    Epigenetics
  2. PARP
  3. TIQ-A

TIQ-A 

Cat. No.: HY-121719 Purity: 99.65%
COA Handling Instructions

TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent.

For research use only. We do not sell to patients.

TIQ-A Chemical Structure

TIQ-A Chemical Structure

CAS No. : 420849-22-5

Size Price Stock Quantity
5 mg USD 200 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
25 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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Description

TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent[1].

IC50 & Target

TNKS2

24 nM (IC50)

PARP2

210 nM (IC50)

PARP15

230 nM (IC50)

PARP10

>10 μM (IC50)

PARP14

>10 μM (IC50)

Molecular Weight

201.24

Formula

C11H7NOS

CAS No.
SMILES

O=C1NC2=C(C3=C1C=CC=C3)C=CS2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (621.15 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9692 mL 24.8460 mL 49.6919 mL
5 mM 0.9938 mL 4.9692 mL 9.9384 mL
10 mM 0.4969 mL 2.4846 mL 4.9692 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
TIQ-A
Cat. No.:
HY-121719
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