AMPK Inhibitors

NUAK1

NUAK2

AMPK

AMPK α1β1γ1

AMPK α2β1γ1

AMPK α1β2γ1

AMPK α2β2γ1

BRSK1

BRSK2

HUNK

AMPKα

AMPK Inhibitors, Agonists & Activators

Product Name	NUAK1	NUAK2	AMPK	AMPK α1β1γ1	AMPK α2β1γ1	AMPK α1β2γ1	AMPK α2β2γ1	BRSK1	BRSK2	HUNK	AMPKα	Purity
Metformin			AMPK									99.98%
Dorsomorphin			AMPK, Ki: 109 nM									99.91%
AICAR			AMPK									99.99%
Dorsomorphin dihydrochloride			AMPK, Ki: 109 nM									99.91%
Metformin hydrochloride			AMPK									99.98%
A-769662			AMPK, EC₅₀: 0.8 μM									99.33%
MK8722			AMPK									99.82%
Bempedoic acid			AMPK									99.97%
[6]-Gingerol			AMPK									99.68%
EX229				AMPK α1β1γ1, Kd: 0.06 μM	AMPK α2β1γ1, Kd: 0.06 μM	AMPK α1β2γ1, Kd: 0.51 μM						99.44%
Phenformin hydrochloride			AMPK									99.64%
AICAR phosphate			AMPK									99.97%
HTH-01-015	NUAK1, IC₅₀: 100 nM											99.10%
Palmitelaidic acid			AMPK									99.4%
WZ4003	NUAK1, IC₅₀: 20 nM	NUAK2, IC₅₀: 100 nM										98.22%
PF-06409577				AMPK α1β1γ1, EC₅₀: 7 nM								99.83%
PF-739				AMPK α1β1γ1, EC₅₀: 8.99 nM	AMPK α2β1γ1, EC₅₀: 5.23 nM	AMPK α1β2γ1, EC₅₀: 126 nM	AMPK α2β2γ1, EC₅₀: 42.2 nM					99.79%
Danthron			AMPK									99.22%
MOTS-c (human)			AMPK									99.90%
MRT199665	NUAK1, IC₅₀: 3 nM	NUAK2, IC₅₀: 120 nM										99.85%
MOTS-c(human) acetate			AMPK									99.74%
Narazaciclib	ARK5, IC₅₀: 5 nM											98.66%
PXL770				AMPK α1β1γ1, EC₅₀: 16.2 nM	AMPK α2β1γ1, EC₅₀: 1338 nM	AMPK α1β2γ1, EC₅₀: 1.3 μM						99.56%
Metformin-d₆ hydrochloride			AMPK									99.98%
8-Chloroadenosine			AMPK									99.75%
ASP4132			AMPK, EC₅₀: 18 nM									99.81%
HTH-02-006		NUAK2, IC₅₀: 126 nM										99.42%
Ginkgolide C			AMPK									99.67%
ZLN024 hydrochloride				AMPK α1β1γ1, EC₅₀: 0.42 μM	AMPK α2β1γ1, EC₅₀: 0.95 μM		AMPK α2β2γ1, EC₅₀: 0.13 μM					98.51%
SAMS			AMPK									98.05%
RSVA405			AMPK, EC₅₀: 1 μM (in cell-based assays)									99.72%
PF-06685249				AMPK α1β1γ1, EC₅₀: 12 nM								98.00%
A17											AMPKα1	99.4%
MT 63-78			AMPK, EC₅₀: 25 μM									98.11%
Ampkinone			AMPK									99.25%
MK-3903			AMPK, EC₅₀: 8 nM									98.03%
Gomisin J			AMPK									99.97%
HDAC11-IN-2				AMPK α1β1γ1								99.52%
Etilefrine			AMPK
AMPK activator 2 hydrochloride			AMPK									99.68%
Myricanol			AMPK									98.93%
YLF-466D			AMPK									99.02%
AMPK activator 1			AMPK, EC₅₀: 0.1 μM									98.53%
AMPK-IN-1							AMPK α2β2γ1, EC₅₀: 551 nM
β-Patchoulene			AMPK
3α-Hydroxymogrol			AMPK									99.88%
IQZ23			AMPK
LRRK2-IN-8	NUAK1, IC₅₀: 10-100 nM
AMPK/mTOR modulator-1			AMPK, Kd: 4.759 μM
AMPKα1 activator 1				AMPK α1β1γ1, IC₅₀: 35.1 nM	AMPK α2β1γ1, IC₅₀: 6200 nM
AMPK activator 9					AMPK α2β1γ1, EC₅₀: 1.1 μM
AMPK activator 8				AMPK α1β1γ1, EC₅₀: 11 nM	AMPK α2β1γ1, EC₅₀: 27 nM	AMPK α1β2γ1, EC₅₀: 4 nM	AMPK α2β2γ1, EC₅₀: 2 nM
NUAK1-IN-3	NUAK1, IC₅₀: 0.49 nM	NUAK2, IC₅₀: 265 nM
VS-II-173			AMPK
AMPK activator 10			AMPK
Tanshinol borneol ester			AMPK
AMPK activator 2			AMPK
ARUK2010489	NUAK1, pIC₅₀: 8.7
LRRK2/NUAK1/TYK2-IN-1	NUAK1
ARUK2010694	NUAK1, pIC₅₀: 8.7
BRSK1 Human Pre-designed siRNA Set A								BRSK1
PF-06679142				AMPK α1β1γ1, EC₅₀: 22 nM
NFAT-133			AMPK
AMPK activator 18							AMPK α2β2γ1, EC₅₀: 17.2 nM
HUNK Human Pre-designed siRNA Set A										HUNK
AMPK-IN-6			AMPK, IC₅₀: 0.093 μM
OICR19451	NUAK1, IC₅₀: 12 nM	NUAK2, IC₅₀: 10 nM
Kazinol B			AMPK
Pinusolide			AMPK									99.93%
Brsk2 Rat Pre-designed siRNA Set A									BRSK2
ZLN024				AMPK α1β1γ1, EC₅₀: 0.42 μM	AMPK α2β1γ1, EC₅₀: 0.95 μM		AMPK α2β2γ1, EC₅₀: 0.13 μM

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