15646-46-5
Chemical Structure
Oxazolone
- CAS No.: 15646-46-5
- Formula:C12H11NO3
- Molecular Weight:217.22
IUPAC Name: (E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one
InChIKey: SJHPCNCNNSSLPL-CSKARUKUSA-N
SMILES: O=C(OC(C1=CC=CC=C1)=N/2)C2=C/OCC
Biological Activity: Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins[1].
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Oxazolone | 98.0% | Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins. | ||||||||||||||||||||
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Keywords
