2. Induced Disease Models Products
  3. Immunology and Inflammatory Disease Models
  4. Hapten

Hapten

Hapten, also known as incomplete antigen, refers to simple small molecule antigen that only has immune response specificity but no immunogenicity, such as certain polysaccharides, lipids, and drugs. The molecular weight of the hapten is too small to stimulate the immune response, and it must bind to the carrier to stimulate the immune response. Haptens have active groups that facilitate coupling with protein carriers, like -COOH, -NH2,-OH, -SH, etc.

Hapten (116):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14649
    Retinoic acid 302-79-4 99.74%
    Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
    Retinoic acid
  • HY-N0583
    Hydrocortisone 50-23-7 99.91%
    Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.
    Hydrocortisone
  • HY-B0141
    Estradiol 50-28-2 99.99%
    Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering.
    Estradiol
  • HY-14519
    Methotrexate 59-05-2 99.75%
    Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
    Methotrexate
  • HY-66019
    FITC 3326-32-7 98.60%
    FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity, excellent fluorescence quantum yield and good water solubility. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm.
    FITC
  • HY-121267
    Dicamba 1918-00-9
    Dicamba is a herbicide with high water solubility and low volatility. Dicamba induces tissue damage and cell death in Gallium aparine L. through lipid peroxidation. Dicamba is widely used in agriculture and horticulture.
    Dicamba
  • HY-157194
    RL-6-Me-7-OH 2184-54-5
    RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC50=25µM). RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research.
    RL-6-Me-7-OH
  • HY-W035214
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde 31906-04-4
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde is a hapten probe.
    Hydroxyisohexyl 3-cyclohexene carboxaldehyde
  • HY-66005
    Acetaminophen 103-90-2 99.98%
    Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen
  • HY-15036
    Diclofenac 15307-86-5 99.92%
    Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
    Diclofenac
  • HY-B0510
    Trimethoprim 738-70-5 99.98%
    Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc.
    Trimethoprim
  • HY-32351
    Calcifediol 19356-17-3 99.94%
    Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent VDR ligand.
    Calcifediol
  • HY-N6615
    Aflatoxin B1 1162-65-8 99.96%
    Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation.
    Aflatoxin B1
  • HY-B2233B
    Phosphorylcholine 3616-04-4 ≥98.0%
    Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties.
    Phosphorylcholine
  • HY-15128
    9-cis-Retinoic acid 5300-03-8 99.32%
    9-cis-Retinoic acid (ALRT1057), a vitamin A derivative, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates cell cycle and has anticancer, anti-inflammatory and neuroprotection activities.
    9-cis-Retinoic acid
  • HY-U00418
    ARS-1620 1698055-85-4 99.62%
    ARS-1620 is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.
    ARS-1620
  • HY-103447
    Zearalenone 17924-92-4 98.50%
    Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts.
    Zearalenone
  • HY-N0337
    Eugenol 97-53-0 99.35%
    Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.
    Eugenol
  • HY-B1025
    Digoxigenin 1672-46-4 99.70%
    Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes.
    Digoxigenin
  • HY-Y0248A
    Farnesol 4602-84-0 99.88%
    Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.
    Farnesol