1. Anti-infection
  2. Bacterial
  3. Levofloxacin

Levofloxacin (Synonyms: (-)-Ofloxacin)

Cat. No.: HY-B0330 Purity: 99.61%
Handling Instructions

Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

For research use only. We do not sell to patients.

Levofloxacin Chemical Structure

Levofloxacin Chemical Structure

CAS No. : 100986-85-4

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10 mM * 1 mL in Water USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 g USD 84 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. Target: Antibacterial Levofloxacin reduced bacterial load compared with placebo by 4.9-fold (95% confidence interval, 1.4-25.7; P=0.02) at day 7 but had no effect at any point on any marker of neutrophilic airway inflammation. In patients with a baseline bacterial load of more than 10(6) cfu/mL, levofloxacin treatment was associated with a 26.5% (95% confidence interval, 1.8%-51.3%; P=0.04) greater reduction in the percentage neutrophil count compared with placebo at day 7 [1]. Levofloxacin was found to significantly improve the clinical and microbiological parameters in CP individuals [2]. A 30-day course of levofloxacin does not significantly improve BK viral load reduction or allograft function when used in addition to overall reduction of immunosuppression [3].

Clinical Trial
Molecular Weight

361.37

Formula

C₁₈H₂₀FN₃O₄

CAS No.

100986-85-4

SMILES

O=C(C(C1=O)=CN2[[email protected]@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (138.36 mM; Need ultrasonic)

DMSO : 10 mg/mL (27.67 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7672 mL 13.8362 mL 27.6725 mL
5 mM 0.5534 mL 2.7672 mL 5.5345 mL
10 mM 0.2767 mL 1.3836 mL 2.7672 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.61%

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Keywords:

Levofloxacin(-)-OfloxacinBacterialInhibitorinhibitorinhibit

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Product name:
Levofloxacin
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HY-B0330
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