1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase Isoform

Topoisomerase

 

Topoisomerase Related Products (94):

Cat. No. Product Name Effect Purity
  • HY-18258
    Berberine chloride
    Inhibitor 99.66%
    Berberine chloride is an alkaloid that acts as an antibiotic.
  • HY-13624A
    Epirubicin hydrochloride
    Inhibitor 99.16%
    Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase.
  • HY-125033
    EIDD-1931
    Inhibitor 99.73%
    EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent.
  • HY-B0330
    Levofloxacin
    Inhibitor 99.84%
    Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria.
  • HY-17577
    Berberine chloride hydrate
    Inhibitor 99.84%
    Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic.
  • HY-B0398
    Nalidixic acid
    Inhibitor 99.99%
    Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria.
  • HY-16742
    Gepotidacin
    Inhibitor 99.29%
    Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor.
  • HY-13631AS
    Exatecan-d5 mesylate
    Inhibitor 99.77%
    Exatecan-d5 mesylate (DX8951f-d5) is deuterium labeled Exatecan mesylate.
  • HY-135867
    NHC-triphosphate
    Inhibitor 99.80%
    NHC-triphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form.
  • HY-135867E
    NHC-triphosphate tetraammonium
    Inhibitor
    NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form.
  • HY-13721
    Phenoxodiol
    Inhibitor 99.76%
    Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis.
  • HY-B1050
    Gemifloxacin mesylate
    Inhibitor 99.84%
    Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic.
  • HY-13061
    Daun02
    Inhibitor 98.85%
    Daun02 is converted by β-galactosidase to Daunorubicin, which is a topoisomerase inhibitor.
  • HY-B0330A
    Levofloxacin hydrate
    Inhibitor 99.28%
    Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria.
  • HY-19024
    Merbarone
    Inhibitor 99.49%
    Merbarone (NSC 336628) is an orally active inhibitor of topoisomerase II.
  • HY-17460A
    Garenoxacin Mesylate hydrate
    Inhibitor 99.78%
    Garenoxacin (BMS284756) Mesylate hydrate is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms.
  • HY-18351
    Indotecan
    Inhibitor ≥98.0%
    Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.
  • HY-12930
    SPR719
    Inhibitor 99.04%
    SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity.
  • HY-13744
    Rubitecan
    Inhibitor 98.07%
    Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells.
  • HY-N6880
    Rabdosiin
    Inhibitor 99.55%
    Rabdosiin is a tetramer of caffeic acid isolated from the stem of Ocimum sanctum.