Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide
Based on 1 Customer Validation
Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide is the drug-linker conjugate for ADC, containing ADC linker Gly-Mal-GGFG and ADC cytotoxin Deruxtecan 2-hydroxypropanamide.
For research use only. We do not sell to patients.
- Purity: 99.01%
- CAS No.: 2750623-07-3
- Formula: C52H55FN10O15
- Molecular Weight:1079.05
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Storage:
-80°C, protect from light
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2750623-07-3
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Appearance Solid
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Molecular Weight 1079.05
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Formula C52H55FN10O15
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Color Light yellow to yellow
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SMILES
OC(CNC[C@H](N1C(C=CC1=O)=O)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C)C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light
Solvent & Solubility
DMSO : 25 mg/mL (23.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light). When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9267 mL | 4.6337 mL | 9.2674 mL | 23.1685 mL |
| 5 mM | 0.1853 mL | 0.9267 mL | 1.8535 mL | 4.6337 mL | |
| 10 mM | 0.0927 mL | 0.4634 mL | 0.9267 mL | 2.3169 mL | |
| 15 mM | 0.0618 mL | 0.3089 mL | 0.6178 mL | 1.5446 mL | |
| 20 mM | 0.0463 mL | 0.2317 mL | 0.4634 mL | 1.1584 mL |