1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topo I Inhibitors

Topo I Inhibitors

Topoisomerase

Topo I

Topo II

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Topo I together.

Please try each isoform separately.

Topo I Specific Inhibitors & Agonists
Product Name Topo I Topo II Topo I Selectivity Purity
Irinotecan
Topoisomerase I
  Selective Inhibitor 99.84%
Camptothecin
Topoisomerase I, IC50: 679 nM
  Selective Inhibitor 98.62%
CH-0793076
Topoisomerase I, IC50: 2.3 μM
  Selective Inhibitor
SN-38
Topoisomerase I
  Selective Inhibitor 99.46%
Topotecan Hydrochloride
Topoisomerase I
  Selective Inhibitor 99.59%
Irinotecan hydrochloride
Topoisomerase I
  Selective Inhibitor 99.75%
Exatecan Mesylate
Topoisomerase I, IC50: 2.2 μM
  Selective Inhibitor 99.56%
β-Lapachone
Topoisomerase I
  Selective Inhibitor 99.98%
Betulinic acid
Topoisomerase I, IC50: 5 μM
  Selective Inhibitor 98.18%
Irinotecan hydrochloride trihydrate
Topoisomerase I
  Selective Inhibitor 99.78%
Dxd
Topoisomerase I, IC50: 0.31 μM
  Selective Inhibitor 98.20%
Genz-644282
Topoisomerase I
  Selective Inhibitor 98.03%
9-amino-CPT
Topoisomerase I
  Selective Inhibitor 98.89%
(S)-10-Hydroxycamptothecin
Topoisomerase I
  Selective Inhibitor 99.38%
Karenitecin
Topoisomerase I
  Selective Inhibitor 98.30%
SW044248
Topoisomerase I
  Selective Inhibitor 99.60%
Namitecan
Topoisomerase I
  Selective Inhibitor
(±)-10-Hydroxycamptothecin
Topoisomerase I
  Selective Inhibitor
LMP744 hydrochloride
Top1
  Selective Inhibitor 99.21%
LMP744
Top1
  Selective Inhibitor
Exatecan
Topoisomerase I, IC50: 2.2 μM
  Selective Inhibitor
Edotecarin
Topoisomerase I, IC50: 50 nM
  Selective Inhibitor 98.39%
Topotecan
Topoisomerase I
  Selective Inhibitor
Podocarpusflavone A
Topoisomerase I, IC50: 119.425 μM
  Selective Inhibitor
TP3011
Topoisomerase I
  Selective Inhibitor
Proscillaridin A
Topoisomerase I, IC50: 30 nM
Topoisomerase II, IC50: 100 nM
Pan Inhibitor 98.38%
TAS-103 dihydrochloride
Topoisomerase I
Topoisomerase II
Pan Inhibitor 99.70%
Belotecan hydrochloride
Top1
  Pan Inhibitor 98.82%
TAS-103
Topoisomerase I
Topoisomerase II
Pan Inhibitor
Zabofloxacin
Topoisomerase I
Topoisomerase II
Pan Inhibitor
Zabofloxacin hydrochloride
Topoisomerase I
Topoisomerase II
Pan Inhibitor
Intoplicine
Topoisomerase I
Topoisomerase II
Pan Inhibitor
Groenlandicine
Topoisomerase I
  default Agonist