1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topo I Inhibitors

Topo I Inhibitors

Topoisomerase

Topo I

Topo II

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform Topo I together.

Please try each isoform separately.

Topo I Specific Inhibitors & Agonists
Product Name Topo I Topo II Topo I Selectivity Purity
Camptothecin
Topoisomerase I, IC50: 679 nM
  Selective Inhibitor 98.26%
SN-38
Topoisomerase I
  Selective Inhibitor 99.46%
(±)-10-Hydroxycamptothecin
Topoisomerase I
  Selective Inhibitor
Topotecan Hydrochloride
Topoisomerase I
  Selective Inhibitor 99.20%
Exatecan Mesylate
Topoisomerase I, IC50: 2.2 μM
  Selective Inhibitor 99.12%
β-Lapachone
Topoisomerase I
  Selective Inhibitor 99.98%
Irinotecan hydrochloride trihydrate
Topoisomerase I
  Selective Inhibitor 99.78%
Dxd
Topoisomerase I, IC50: 0.31 μM
  Selective Inhibitor 98.20%
Genz-644282
Topoisomerase I
  Selective Inhibitor 98.03%
9-amino-CPT
Topoisomerase I
  Selective Inhibitor 98.89%
Karenitecin
Topoisomerase I
  Selective Inhibitor 98.30%
SW044248
Topoisomerase I
  Selective Inhibitor 99.60%
LMP744 hydrochloride
Top1
  Selective Inhibitor 99.21%
LMP744
Top1
  Selective Inhibitor
Exatecan
Topoisomerase I, IC50: 2.2 μM
  Selective Inhibitor
Edotecarin
Topoisomerase I, IC50: 50 nM
  Selective Inhibitor 98.39%
Topotecan
Topoisomerase I
  Selective Inhibitor
Podocarpusflavone A
Topoisomerase I, IC50: 119.425 μM
  Selective Inhibitor
Namitecan
Topoisomerase I
  Selective Inhibitor
TAS-103 dihydrochloride
Topoisomerase I
Topoisomerase II
Pan Inhibitor 99.70%
Belotecan hydrochloride
Top1
  Pan Inhibitor 98.80%
TAS-103
Topoisomerase I
Topoisomerase II
Pan Inhibitor
Intoplicine
Topoisomerase I
Topoisomerase II
Pan Inhibitor
Groenlandicine
Topoisomerase I
  default Agonist