Mal-Gly-PAB-Exatecan-D-glucuronic acid

Cat. No.: HY-153179 Purity: 99.20%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis.

For research use only. We do not sell to patients.

Mal-Gly-PAB-Exatecan-D-glucuronic acid Chemical Structure

CAS No. : 2763252-25-9

Size	Price	Stock	Quantity
5 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 880	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1750	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 2820	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 4500	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Mal-Gly-PAB-Exatecan-D-glucuronic acid:

M3554 Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis^[1].

Molecular Weight

984.89

Formula

C₄₇H₄₅FN₆O₁₇

CAS No.

2763252-25-9

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C=CC1=O)N1CCC(NCC(NC(C=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=C(C=C2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)C(O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (101.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0153 mL	5.0767 mL	10.1534 mL
5 mM	0.2031 mL	1.0153 mL	2.0307 mL
10 mM	0.1015 mL	0.5077 mL	1.0153 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (278 KB) SDS (252 KB)

COA (268 KB) HNMR (189 KB) LCMS (103 KB)

Handling Instructions (2659 KB)

References

[1]. Anderl Jan, et al. Anti-CEACAM5 antibodies and conjugates and uses thereof. World Intellectual Property Organization, WO2022048883 A1. 2022-03-10.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0153 mL	5.0767 mL	10.1534 mL	25.3835 mL
	5 mM	0.2031 mL	1.0153 mL	2.0307 mL	5.0767 mL
	10 mM	0.1015 mL	0.5077 mL	1.0153 mL	2.5384 mL
	15 mM	0.0677 mL	0.3384 mL	0.6769 mL	1.6922 mL
	20 mM	0.0508 mL	0.2538 mL	0.5077 mL	1.2692 mL
	25 mM	0.0406 mL	0.2031 mL	0.4061 mL	1.0153 mL
	30 mM	0.0338 mL	0.1692 mL	0.3384 mL	0.8461 mL
	40 mM	0.0254 mL	0.1269 mL	0.2538 mL	0.6346 mL
	50 mM	0.0203 mL	0.1015 mL	0.2031 mL	0.5077 mL
	60 mM	0.0169 mL	0.0846 mL	0.1692 mL	0.4231 mL
	80 mM	0.0127 mL	0.0635 mL	0.1269 mL	0.3173 mL
	100 mM	0.0102 mL	0.0508 mL	0.1015 mL	0.2538 mL