Mal-Gly-PAB-Exatecan-D-glucuronic acid
Based on 1 Customer Validation
Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis.
For research use only. We do not sell to patients.
- Purity : 98.98%
- CAS No.: 2763252-25-9
- Formula: C47H45FN6O17
- Molecular Weight:984.89
-
Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
HY-147271
Mal-PEG8-Val-Ala-PAB-Exatecan -
HY-145929
MC-Val-Cit-PAB-Exatecan -
HY-15575
VcMMAE -
HY-136317
MC-betaglucuronide-MMAE-1 -
HY-114233
MC-GGFG-Exatecan -
HY-147270
MC-VA-PAB-Exatecan -
HY-13631E
Deruxtecan -
HY-147239
MC-VA-PABC-MMAE -
HY-15741
Mc-MMAE -
HY-128946
CL2A-SN-38 -
HY-13631
Exatecan -
HY-141156
Mal-PEG8-Val-Cit-PAB-MMAE
Biological Activity
Description
IC50 & Target
|
Camptothecins |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2763252-25-9
-
Appearance Solid
-
Molecular Weight 984.89
-
Formula C47H45FN6O17
-
Color Light yellow to green yellow
-
SMILES
O=C(C=CC1=O)N1CCC(NCC(NC(C=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=C(C=C2)O[C@@H]9O[C@@H]([C@H]([C@@H]([C@H]9O)O)O)C(O)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (101.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (281 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0153 mL | 5.0767 mL | 10.1534 mL | 25.3835 mL |
| 5 mM | 0.2031 mL | 1.0153 mL | 2.0307 mL | 5.0767 mL | |
| 10 mM | 0.1015 mL | 0.5077 mL | 1.0153 mL | 2.5384 mL | |
| 15 mM | 0.0677 mL | 0.3384 mL | 0.6769 mL | 1.6922 mL | |
| 20 mM | 0.0508 mL | 0.2538 mL | 0.5077 mL | 1.2692 mL | |
| 25 mM | 0.0406 mL | 0.2031 mL | 0.4061 mL | 1.0153 mL | |
| 30 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8461 mL | |
| 40 mM | 0.0254 mL | 0.1269 mL | 0.2538 mL | 0.6346 mL | |
| 50 mM | 0.0203 mL | 0.1015 mL | 0.2031 mL | 0.5077 mL | |
| 60 mM | 0.0169 mL | 0.0846 mL | 0.1692 mL | 0.4231 mL | |
| 80 mM | 0.0127 mL | 0.0635 mL | 0.1269 mL | 0.3173 mL | |
| 100 mM | 0.0102 mL | 0.0508 mL | 0.1015 mL | 0.2538 mL |
Mal-Gly-PAB-Exatecan-D-glucuronic acid Related Classifications
HY-153179 Related Classifications
Powered by Bioz