Mal-PEG8-Val-Ala-PAB-Exatecan
Based on 1 Customer Validation
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research.
For research use only. We do not sell to patients.
- Purity: 99.48%
- CAS No.: 2679821-39-5
- Formula: C66H85FN8O20
- Molecular Weight:1329.42
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Camptothecins |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2679821-39-5
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Appearance Solid
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Molecular Weight 1329.42
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Formula C66H85FN8O20
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Color Off-white to light yellow
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SMILES
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (75.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7522 mL | 3.7610 mL | 7.5221 mL | 18.8052 mL |
| 5 mM | 0.1504 mL | 0.7522 mL | 1.5044 mL | 3.7610 mL | |
| 10 mM | 0.0752 mL | 0.3761 mL | 0.7522 mL | 1.8805 mL | |
| 15 mM | 0.0501 mL | 0.2507 mL | 0.5015 mL | 1.2537 mL | |
| 20 mM | 0.0376 mL | 0.1881 mL | 0.3761 mL | 0.9403 mL | |
| 25 mM | 0.0301 mL | 0.1504 mL | 0.3009 mL | 0.7522 mL | |
| 30 mM | 0.0251 mL | 0.1254 mL | 0.2507 mL | 0.6268 mL | |
| 40 mM | 0.0188 mL | 0.0940 mL | 0.1881 mL | 0.4701 mL | |
| 50 mM | 0.0150 mL | 0.0752 mL | 0.1504 mL | 0.3761 mL | |
| 60 mM | 0.0125 mL | 0.0627 mL | 0.1254 mL | 0.3134 mL |
Mal-PEG8-Val-Ala-PAB-Exatecan Related Classifications
HY-147271 Related Classifications
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