Mal-PEG8-Val-Cit-PAB-MMAE
Based on 1 Customer Validation
Mal-PEG8-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAE contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162).
For research use only. We do not sell to patients.
- Purity: 97.12%
- CAS No.: 3058970-85-4
- Formula: C81H131N11O23
- Molecular Weight:1626.97
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Storage:
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3058970-85-4
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Appearance Solid
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Molecular Weight 1626.97
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Formula C81H131N11O23
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Color White to off-white
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SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : 110 mg/mL (67.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6146 mL | 3.0732 mL | 6.1464 mL | 15.3660 mL |
| 5 mM | 0.1229 mL | 0.6146 mL | 1.2293 mL | 3.0732 mL | |
| 10 mM | 0.0615 mL | 0.3073 mL | 0.6146 mL | 1.5366 mL | |
| 15 mM | 0.0410 mL | 0.2049 mL | 0.4098 mL | 1.0244 mL | |
| 20 mM | 0.0307 mL | 0.1537 mL | 0.3073 mL | 0.7683 mL | |
| 25 mM | 0.0246 mL | 0.1229 mL | 0.2459 mL | 0.6146 mL | |
| 30 mM | 0.0205 mL | 0.1024 mL | 0.2049 mL | 0.5122 mL | |
| 40 mM | 0.0154 mL | 0.0768 mL | 0.1537 mL | 0.3841 mL | |
| 50 mM | 0.0123 mL | 0.0615 mL | 0.1229 mL | 0.3073 mL | |
| 60 mM | 0.0102 mL | 0.0512 mL | 0.1024 mL | 0.2561 mL |
Mal-PEG8-Val-Cit-PAB-MMAE Related Classifications
HY-141156 Related Classifications
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