1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Mal-PEG8-Val-Cit-PAB-MMAE

Mal-PEG8-Val-Cit-PAB-MMAE 

Cat. No.: HY-141156
Handling Instructions

Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Mal-PEG8-Val-Cit-PAB-MMAE Chemical Structure

Mal-PEG8-Val-Cit-PAB-MMAE Chemical Structure

CAS No. : 2353409-69-3

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Description

Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

1626.97

Formula

C₈₁H₁₃₁N₁₁O₂₃

CAS No.

2353409-69-3

SMILES

CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C(OCC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Mal-PEG8-Val-Cit-PAB-MMAEADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Mal-PEG8-Val-Cit-PAB-MMAE
Cat. No.:
HY-141156
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