1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topo II Isoform

Topo II

 

Topo II Related Products (79):

Cat. No. Product Name Effect Purity
  • HY-15142
    Doxorubicin hydrochloride
    Inhibitor 99.58%
    Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent.
  • HY-13629
    Etoposide
    Inhibitor 99.94%
    Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent.
  • HY-13062
    Daunorubicin hydrochloride
    Inhibitor 99.23%
    Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity.
  • HY-13502
    Mitoxantrone
    Inhibitor 98.36%
    Mitoxantrone is a potent topoisomerase II inhibitor.
  • HY-17381
    Idarubicin hydrochloride
    Inhibitor 99.83%
    Idarubicin hydrochloride is an anthracycline antileukemic drug.
  • HY-13502B
    Mitoxantrone diacetate
    Inhibitor
    Mitoxantrone diacetate is a potent topoisomerase II inhibitor.
  • HY-17381A
    Idarubicin
    Inhibitor
    Idarubicin is an orally active and potent anthracycline antileukemic agent.
  • HY-108876
    Daunorubicin citrate
    Inhibitor
    Daunorubicin (Daunomycin) citrate is a topoisomerase II inhibitor with potent anti-tumor activity.
  • HY-16261
    Aldoxorubicin
    Inhibitor
    Aldoxorubicin (INNO-206) is an albumin-binding prodrug of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions.
  • HY-13725
    Pirarubicin
    Inhibitor 99.61%
    Pirarubicin is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
  • HY-13562A
    Banoxantrone dihydrochloride
    Inhibitor 99.17%
    Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
  • HY-13502A
    Mitoxantrone dihydrochloride
    Inhibitor 99.55%
    Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor.
  • HY-100875
    Bisantrene
    Inhibitor
    Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation.
  • HY-N2306A
    Aclacinomycin A hydrochloride
    Inhibitor
    Aclacinomycin A (Aclarubicin) hydrochloride is an orally active and potent anthracycline antitumor antibiotic.
  • HY-13761
    Teniposide
    Inhibitor 98.88%
    Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent.
  • HY-13725A
    Pirarubicin Hydrochloride
    Inhibitor 98.51%
    Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
  • HY-122575
    Aurintricarboxylic acid
    Inhibitor
    Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively.
  • HY-B1099
    Hycanthone
    Inhibitor 99.73%
    Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II.
  • HY-106662
    Chloroquinoxaline sulfonamide
    Inhibitor 99.47%
    Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison.
  • HY-15753A
    Ellipticine hydrochloride
    Inhibitor 99.45%
    Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.