2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial DNA/RNA Synthesis
  4. Lavofloxacin lactate

Lavofloxacin lactate  (Synonyms: (-)-Ofloxacin lactate)

Cat. No.: HY-B0013
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Lavofloxacin lactate ((-)-ofloxacin lactate) is a class of broad-spectrum antimicrobials that can kill or inhibit a variety of bacteria. Lavofloxacin lactate binds to DNA rotase and topoisomerase IV, resulting in blocked DNA replication and repair, thus inhibiting bacterial growth. Lavofloxacin lactate can be used to study resistance mechanisms in bacteria, including studying resistance genes and mutations.

For research use only. We do not sell to patients.

CAS No. : 294662-18-3

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Lavofloxacin lactate Related Antibodies

Top Publications Citing Use of Products

32 Publications Citing Use of MCE Lavofloxacin lactate

Microbiological Assay
Cell Proliferation/Viability Assay

    Lavofloxacin lactate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 May 10;16(1):4366.  [Abstract]

    M. bovis BCG Russia WT in LFX (0-25 h) 1 mg/L.

    Lavofloxacin lactate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 May 10;16(1):4366.  [Abstract]

    M. bovisBCG Russia FQR in LFX (0-25 h) 1 mg/L.

    Lavofloxacin lactate purchased from MedChemExpress. Usage Cited in: Acta Pharm Sin B. 2025 Dec;15(12):6382-6398.

    Levofloxacin exhibited toxicity at 25 × Cmax, which resulted in a 65% reduction in organoid cell viability.

    Lavofloxacin lactate purchased from MedChemExpress. Usage Cited in: EBioMedicine. 2025 May 30:117:105776.  [Abstract]

    Killing curves of different Ms rpoB mutants after exposure to LFX (0-48 h) at 1 μg/mL (5 × MIC) in 7H9 medium.

    Lavofloxacin lactate purchased from MedChemExpress. Usage Cited in: Antibiotics (Basel). 2022 Feb 1;11(2):192.

    Determined minimum inhibitory concentrations (MICs) of Gepotidacin, Levofloxacin, Moxifloxacin, and Co-trimoxazole against S. maltophilia.

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    Description

    Lavofloxacin lactate ((-)-ofloxacin lactate) is a class of broad-spectrum antimicrobials that can kill or inhibit a variety of bacteria. Lavofloxacin lactate binds to DNA rotase and topoisomerase IV, resulting in blocked DNA replication and repair, thus inhibiting bacterial growth. Lavofloxacin lactate can be used to study resistance mechanisms in bacteria, including studying resistance genes and mutations[1].

    Clinical Trial
    Molecular Weight

    451.45

    Formula

    C21H26FN3O7
    CAS No.
    SMILES

    O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O.CC(O)C(O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Lavofloxacin lactate Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Lavofloxacin294662-18-3(-)-OfloxacinBacterialDNA/RNA SynthesisBacterial killingresistance mechanismbroad spectrumtopoisomerase IVInhibitorinhibitorinhibit

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