1. Metabolic Enzyme/Protease
  2. Acyltransferase
  3. Fumonisin B1

Fumonisin B1 

Cat. No.: HY-N6719
Handling Instructions

Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin.

For research use only. We do not sell to patients.

Fumonisin B1 Chemical Structure

Fumonisin B1 Chemical Structure

CAS No. : 116355-83-0

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Description

Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[1][2].

IC50 & Target

Sphingosine N-acyltransferase[2]

In Vitro

Fumonisin B1 alters the gene expression and signal transduction pathways in monkey kidney cells[3].
Fumonisin B1 increases the initial disruption of sphingolipid metabolism and the accumulation of sphinganine in LLC-PK1 kidney cells, causes DNA damage of apoptotic type in rat astrocytes[3].

Molecular Weight

721.83

Formula

C₃₄H₅₉NO₁₅

CAS No.

116355-83-0

SMILES
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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Fumonisin B1
Cat. No.:
HY-N6719
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