Acyltransferase Inhibitors

ACAT1

ACAT2

MGAT2

ACAT

DGAT1

DGAT2

Acyltransferase Inhibitors

Product Name	ACAT1	ACAT2	MGAT2	ACAT	DGAT1	DGAT2	Purity
Avasimibe	ACAT1, IC₅₀: 24 μM	ACAT2, IC₅₀: 9.2 μM					99.85%
447C88				ACAT, IC₅₀: 23 nM
K-604 dihydrochloride	ACAT-1, IC₅₀: 0.45 μM	ACAT-2, IC₅₀: 102.85 μM					99.42%
Nevanimibe hydrochloride	ACAT1, EC₅₀: 9 nM	ACAT2, EC₅₀: 368 nM					99.49%
Glabrol				ratACAT, IC₅₀: 24.6 μM			99.83%
Pactimibe	ACAT1, IC₅₀: 4.9 μM	ACAT2, IC₅₀: 3.0 μM		ACAT, IC₅₀: 2 μM (in the liver) ACAT, IC₅₀: 2.7 μM (in macrophages) ACAT, IC₅₀: 4.7 μM (in THP-1 cells)			99.98%
Enniatin B1				ACAT			99.34%
VULM 1457				ACAT			99.71%
Nevanimibe	ACAT1, EC₅₀: 9 nM	ACAT2, EC₅₀: 368 nM					98.99%
Pactimibe sulfate	ACAT1, IC₅₀: 4.9 μM	ACAT2, IC₅₀: 3.0 μM		ACAT, IC₅₀: 2 μM (in the liver) ACAT, IC₅₀: 2.7 μM (in macrophages) ACAT, IC₅₀: 4.7 μM (in THP-1 cells)			98.0%
Enniatin B				ACAT			99.86%
S-309309			MGAT2				98.55%
Esculeogenin A	ACAT-1	ACAT-2
MGAT2-IN-2			MGAT2, IC₅₀: 3.4 nM
DGAT1-IN-4					DGAT1, IC₅₀: 17 nM	DGAT2, IC₅₀: >10 μM
CL-283796				ACAT
Phenylpyropene C				ACAT, IC₅₀: 16.0 μM
Ilekudinol B				ACAT
Ent-Calquiquelignan E					DGAT1, IC₅₀: 71.5 μM
Enniatin A				ACAT
MGAT2-IN-6			MGAT2

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