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  4. Phosphorylcholine

Phosphorylcholine  (Synonyms: Phosphocholine)

Cat. No.: HY-B2233B Purity: ≥98.0%
COA Handling Instructions

Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties.

For research use only. We do not sell to patients.

Phosphorylcholine Chemical Structure

Phosphorylcholine Chemical Structure

CAS No. : 3616-04-4

Size Price Stock Quantity
Oil + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 22 In-stock
Solution
10 mM * 1 mL in Water USD 22 In-stock
Oil
100 mg USD 20 In-stock
500 mg USD 40 In-stock
1 g   Get quote  
5 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of Phosphorylcholine:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties[1].

IC50 & Target

Human Endogenous Metabolite

 

Microbial Metabolite

 

Molecular Weight

183.14

Formula

C5H14NO4P

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O=P(OCC[N+](C)(C)C)([O-])O

Structure Classification
Initial Source

a variety of prokaryotic and eukaryotic pathogens

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (546.03 mM; Need ultrasonic)

Ethanol : 4 mg/mL (21.84 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4603 mL 27.3015 mL 54.6030 mL
5 mM 1.0921 mL 5.4603 mL 10.9206 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (546.03 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / H2O 1 mM 5.4603 mL 27.3015 mL 54.6030 mL 136.5076 mL
5 mM 1.0921 mL 5.4603 mL 10.9206 mL 27.3015 mL
10 mM 0.5460 mL 2.7302 mL 5.4603 mL 13.6508 mL
15 mM 0.3640 mL 1.8201 mL 3.6402 mL 9.1005 mL
20 mM 0.2730 mL 1.3651 mL 2.7302 mL 6.8254 mL
H2O 25 mM 0.2184 mL 1.0921 mL 2.1841 mL 5.4603 mL
30 mM 0.1820 mL 0.9101 mL 1.8201 mL 4.5503 mL
40 mM 0.1365 mL 0.6825 mL 1.3651 mL 3.4127 mL
50 mM 0.1092 mL 0.5460 mL 1.0921 mL 2.7302 mL
60 mM 0.0910 mL 0.4550 mL 0.9101 mL 2.2751 mL
80 mM 0.0683 mL 0.3413 mL 0.6825 mL 1.7063 mL
100 mM 0.0546 mL 0.2730 mL 0.5460 mL 1.3651 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phosphorylcholine
Cat. No.:
HY-B2233B
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