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Phosphorylcholine chloride

(Synonyms: Phosphocholine chloride)
12 Cited Publications
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Based on 12 publication(s) in Google Scholar

Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties.

For research use only. We do not sell to patients.

  • Purity: 99.95%
  • CAS No.: 107-73-3
  • Formula: C5H15ClNO4P
  • Molecular Weight:219.60
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Phosphorylcholine chloride Chemical Structure
    Phosphorylcholine chloride Chemical Structure
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
  • Experimental Validation Results for Phosphorylcholine chloride
CAS No.: 107-73-3
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  • Phosphorylcholine chloride Chemical Structure
    Phosphorylcholine chloride Chemical Structure
    1/16
  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Immunity. 2025 Nov 11;58(11):2670-2684.e10. [Abstract]

    Customer Validation
     Phosphorylcholine (PC, 10 μM; 24 h) increased HSV-1-induced cGAS-STING signaling and reduced HSV-1 replication in L929 cells.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Immunity. 2025 Nov 11;58(11):2670-2684.e10. [Abstract]

    Customer Validation
     SMPDL3B (5 μM) were pre-incubated with Phosphorylcholine (PC, 100 μM) or ENPP1-1-IN-14 (100 μM) at 4°C for 30 min, and then incubated with cGAMP (100 μM) at 37°C for 3 h. The concentration of cGAMP was examined by cGAMP ELISA kit.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Immunity. 2025 Nov 11;58(11):2670-2684.e10. [Abstract]

    Customer Validation
     SMPDL3B was pre-incubated with or without Phosphorylcholine (PC, 10 μM) at 4°C for 1 h, and then incubated with or without cGAMP (100 μM) at 37°C for 4 h. RAW-Lucia ISG cells were stimulated with the above reaction products (50-fold dilution) for 24 h and the ISRE reporter activity was assessed following the standard protocol.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Microbiome. 2025 Apr 2;13(1):90. [Abstract]

    Customer Validation
     The pig intestines of the Phosphorylcholine (PC) (10 mg/kg; once daily for 8 days) pretreatment group exhibited mild congestion and edema in gut appearance, while the PEDV group showed obvious lesions and severe congestion and edema.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Microbiome. 2025 Apr 2;13(1):90. [Abstract]

    Customer Validation
     Phosphorylcholine (PC) (10 mg/kg; once daily for 8 d) mitigated the negative impacts of intestinal virus, as evidenced by improved survival rates and body weight changes, and alleviated broken villi and extensive epithelial cell shedding in piglets.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Microbiome. 2025 Apr 2;13(1):90. [Abstract]

    Customer Validation
     Phosphorylcholine (PC) (1, 5, and 10 μM; 24 h) treatment at different concentrations inhibited PEDV-induced cell death in both IPEC-J2 and Vero cells.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Microbiome. 2025 Apr 2;13(1):90. [Abstract]

    Customer Validation
     Expression analysis of RIPK1, p-RIPK1, RIPK3, p-RIPK3, MLKL, p-MLKL, and PEDV-N in IPEC-J2 cells pre-treated with various Phosphorylcholine (PC) (1, 5, and 10 μM) concentrations post-PEDV infection. Phosphorylcholine (PC) (1, 5, and 10 μM) treatment reduced the phosphorylation levels of RIPK1, RIPK3, and MLKL.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: Microbiome. 2025 Apr 2;13(1):90. [Abstract]

    Customer Validation
     Phosphorylcholine (PC) (10 mg/kg; once daily for 8 days) pretreatment alleviated viral infection of the pig's intestines, keeping the intestinal villi and tissue structure intact, with only minor damage and epithelial cell shedding.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: NPJ Biofilms Microbiomes. 2023 Sep 4;9(1):62. [Abstract]

    Customer Validation
     Fecal water content and fecal Na+ content; C57BL/6 male mice were either orally administrated with 0.1 mL PBS (CONT group) or 0.1  mL Phosphorylcholine at a concentration of 2.5 mol/L (PC group) for 7 days. The results showed that that Phosphorylcholine increased fecal water and Na+ content.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: NPJ Biofilms Microbiomes. 2023 Sep 4;9(1):62. [Abstract]

    Customer Validation
     Colonic morphology (Scale bar = 200 μm; arrows, impaired villus). The results showed that Phosphorylcholine (Phosphocholine, 2.5 mol/L; 0.1  mL; i.g.; once daily for 7 days) protected mice from morphological damage.

  • 1/16

    Phosphorylcholine chloride purchased from MedChemExpress. Usage Cited in: NPJ Biofilms Microbiomes. 2023 Sep 4;9(1):62. [Abstract]

    Customer Validation
     Phosphorylcholine (Phosphocholine, 2.5 mol/L; 0.1 mL; i.g.; once daily for 7 days) alleviated C. rodentium-induced apoptosis, as indicated by decreased caspase-3 expression (Fig. n), and epithelial proliferation, as indicated by decreased Ki67 expression (Fig. o).

  • Phosphorylcholine chloride