2. Disease Areas
  3. Inflammation or Immune System Disease
  4. Genitourinary Inflammation
  5. Urinary Tract Infections

Urinary Tract Infections

Urinary Tract Infections (UTIs) are common bacterial infections that affect any part of the urinary system, including the kidneys, ureters, bladder, and urethra. Most UTIs involve the lower urinary tract, particularly the bladder (cystitis) and urethra (urethritis). They are primarily caused by bacteria, most commonly Escherichia coli, which enter the urinary tract through the urethra. Symptoms may include dysuria, frequent urination, urgency, suprapubic pain, and cloudy or bloody urine. Risk factors include female anatomy, sexual activity, menopause, urinary retention, catheter use, and underlying medical conditions such as diabetes. Diagnosis is typically based on clinical symptoms and urinalysis, with urine culture used to confirm the causative organism and guide antibiotic therapy. Treatment involves antibiotics tailored to the severity and location of infection, with prompt management crucial to prevent complications like pyelonephritis or sepsis. Prevention strategies include adequate hydration, proper hygiene, voiding after intercourse, and avoiding irritants such as harsh soaps or douches. Recurrent UTIs may require further evaluation for anatomical or functional abnormalities.

Urinary Tract Infections (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-18257
    Rolitetracycline 751-97-3 ≥98.0%
    Rolitetracycline is a highly soluble, broad-spectrum antibiotic derived from tetracycline. Rolitetracycline binds to and stabilizes bovine serum albumin, and also inhibits HIV-1 integrase, blocks Aβ fibril formation and suppresses dengue virus proliferation. Rolitetracycline mediates the inhibition of Aβ fibrils via a specific three-dimensional pharmacophore conformation, and exerts bacteriostatic and bactericidal activities. Rolitetracycline acts synergistically with Penicillin G (HY-N7139) or Cephalothin (HY-B1275A) to alter the effects on microbial growth. Rolitetracycline serves as an important tool compound for the study of bacterial infections (urinary tract infections, sepsis), HIV-1 and dengue virus infections, as well as Alzheimer's disease.
    Rolitetracycline
  • HY-B1387
    Sulfamethoxypyridazine 80-35-3 99.93%
    Sulfamethoxypyridazine is an orally active and brain-penetrant sulfonamide antibiotic. Sulfamethoxypyridazine exhibits antibacterial activity and inhibits growth of susceptible bacterial strains. Sulfamethoxypyridazine can be used for the research of pyelonephritis, urinary tract infections, and dermatitis herpetiformis.
    Sulfamethoxypyridazine