Sulfamethoxypyridazine
Based on 1 Customer Validation
Sulfamethoxypyridazine is an orally active and brain-penetrant sulfonamide antibiotic. Sulfamethoxypyridazine exhibits antibacterial activity and inhibits growth of susceptible bacterial strains. Sulfamethoxypyridazine can be used for the research of pyelonephritis, urinary tract infections, and dermatitis herpetiformis.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 80-35-3
- Formula: C11H12N4O3S
- Molecular Weight:280.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Sulfamethoxypyridazine is absorbed rapidly from the gastrointestinal tract[1].
Sulfamethoxypyridazine has a high diffusion capacity in cerebrospinal fluid[1].
Sulfamethoxypyridazine inhibits the growth of 98 mixed bacterial species strains in vitro, with complete inhibition of all strains occurring at concentrations greater than 300 mg/100 cc[2].
Sulfamethoxypyridazine exhibits the highest in vitro activity against Staphylococcus aureus, B. proteus, and E. coli strains, with lower activity against A. aerogenes, paracolon bacillus, and P. aeruginosa strains[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 80-35-3
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Appearance Solid
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Molecular Weight 280.30
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Formula C11H12N4O3S
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Color White to off-white
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SMILES
O=S(C1=CC=C(N)C=C1)(NC2=NN=C(OC)C=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : ≥ 42 mg/mL (149.84 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5676 mL | 17.8380 mL | 35.6761 mL | 89.1902 mL |
| 5 mM | 0.7135 mL | 3.5676 mL | 7.1352 mL | 17.8380 mL | |
| 10 mM | 0.3568 mL | 1.7838 mL | 3.5676 mL | 8.9190 mL | |
| 15 mM | 0.2378 mL | 1.1892 mL | 2.3784 mL | 5.9460 mL | |
| 20 mM | 0.1784 mL | 0.8919 mL | 1.7838 mL | 4.4595 mL | |
| 25 mM | 0.1427 mL | 0.7135 mL | 1.4270 mL | 3.5676 mL | |
| 30 mM | 0.1189 mL | 0.5946 mL | 1.1892 mL | 2.9730 mL | |
| 40 mM | 0.0892 mL | 0.4460 mL | 0.8919 mL | 2.2298 mL | |
| 50 mM | 0.0714 mL | 0.3568 mL | 0.7135 mL | 1.7838 mL | |
| 60 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.4865 mL | |
| 80 mM | 0.0446 mL | 0.2230 mL | 0.4460 mL | 1.1149 mL | |
| 100 mM | 0.0357 mL | 0.1784 mL | 0.3568 mL | 0.8919 mL |
Sulfamethoxypyridazine Related Classifications
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