2. Induced Disease Models Products
  3. Immunology and Inflammatory Disease Models
  4. Gastrointestinal Inflammation and Ulcer Models
  5. Inflammatory Bowel Disease (IBD) Models

Inflammatory Bowel Disease (IBD) Models

Inflammatory Bowel Disease (IBD) Models (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-116282C
    Dextran sulfate sodium salt (MW 35000-45000) 9011-18-1
    Dextran sulfate sodium salt (MW 35000-45000) is a polymer of anhydroglucose with the molecular weight range of 35000-45000. Dextran sulfate sodium salt can be used to induce colitis. Dextran sulfate sodium salt also can inhibit the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells.
    Dextran sulfate sodium salt (MW 35000-45000)
  • HY-126360
    Oxazolone 15646-46-5 ≥98.0%
    Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins.
    Oxazolone