125-10-0
125-10-0
Chemical Structure
Prednisone acetate
Synonym(s): Prednisone 21-acetate
- CAS No.: 125-10-0
- Formula:C23H28O6
- Molecular Weight:400.46
IUPAC Name: 2-((8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
InChIKey: MOVRKLZUVNCBIP-RFZYENFJSA-N
SMILES: C[C@@]1(C2)[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O
Biological Activity: Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].
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Prednisone acetate | 99.92% | Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response. | ||||||||||||||||||||
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Prednisone acetate (Standard) | ≥98% | Prednisone acetate (Standard) is the analytical standard of Prednisone acetate. This product is intended for research and analytical applications. Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response. | ||||||||||||||||||||
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Prednisone acetate-d3 | 96.47% | Prednisone acetate-d3 is the deuterium labeled Prednisone acetate. Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties. | ||||||||||||||||||||
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References
- [1]. Wang Y, et al. Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation [J]. Brain Research, 2023, 1805: 148270.
- [2]. Zhou M, Qu R, Yin X, et al. Prednisone acetate modulates Th1/Th2 and Th17/Treg cell homeostasis in experimental autoimmune uveitis via orchestrating the Notch signaling pathway [J]. International Immunopharmacology, 2023, 116: 109809.
