1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Epigenetics
  3. Sirtuin
  4. Sirtuin Isoform

Sirtuin

 

Sirtuin Related Products (32):

Cat. No. Product Name Effect Purity
  • HY-15452
    Selisistat
    Inhibitor 99.87%
    Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC50 of 123 nM for SirT1.
  • HY-N0182
    Fisetin
    Activator 98.91%
    Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
  • HY-112634
    SIRT5 inhibitor 1
    Inhibitor ≥98.0%
    SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
  • HY-112587
    MC3482
    Inhibitor 99.90%
    MC3482 is a specific sirtuin5 (SIRT5) inhibitor.
  • HY-133998
    SIRT-IN-3
    Inhibitor 99.12%
    SIRT-IN-3 is a potent SIRT inhibitor, with an IC50 of 17 μM for SIRT1.
  • HY-13423
    Tenovin-1
    Inhibitor 99.88%
    Tenovin-1, a p53 activator, protects p53 from MDM2-mediated degradation.
  • HY-152090
    Antiproliferative agent-17
    Inhibitor
    Antiproliferative agent-17 is an antiproliferative agent.
  • HY-151488
    CypD-IN-4
    Inhibitor
    CypD-IN-4 is a potent and subtype-selective cyclophilin D (CypD) inhibitor.
  • HY-139742
    ADTL-SA1215
    Activator 99.18%
    ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer.
  • HY-108986
    JFD00244
    Inhibitor 98.03%
    JFD00244 is a sirtuin 2 (SIRT2) inhibitor, with anti-tumor effect.
  • HY-15452B
    (R)-Selisistat
    98.37%
    (R)-Selisistat ((R)-EX-527) is a R-enantiomer of Selisistat.
  • HY-136203
    Resveratrol analog 1
    Agonist 98.06%
    Resveratrol analog 1 is an analog of Resveratrol (HY-16561), compound 48.
  • HY-124113
    4'-Bromo-resveratrol
    Inhibitor 99.79%
    4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3.
  • HY-B0150S
    Nicotinamide-d4
    Inhibitor 99.37%
    Nicotinamide-d4 (Niacinamide-d4) is the deuterium labeled Nicotinamide.
  • HY-W020111
    7-Chloro-4-(piperazin-1-yl)quinoline
    Inhibitor
    7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry.
  • HY-151522
    SIRT2-IN-10
    Inhibitor
    SIRT2-IN-10 (Compound 12) is a potent SIRT2 inhibitor with an IC50 of 1.3 μM.
  • HY-16561S1
    Resveratrol-13C6
    Activator
  • HY-P0096
    Decapeptide-12
    Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM).
  • HY-151487
    CypD-IN-3
    Inhibitor
    CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor.
  • HY-151185
    Sirt2-IN-7
    Inhibitor
    Sirt2-IN-7 (compound 22) is a selective inhibitor of SIRT2.