1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    Metabolic Enzyme/Protease
  2. GABA Receptor
    Endogenous Metabolite
  3. Propofol

Propofol (Synonyms: 2,6-Diisopropylphenol)

Cat. No.: HY-B0649 Purity: 99.88%
Handling Instructions

Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic.

For research use only. We do not sell to patients.

Propofol Chemical Structure

Propofol Chemical Structure

CAS No. : 2078-54-8

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Based on 1 publication(s) in Google Scholar

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Description

Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Propofol (i.p.; 40 mg/kg) causes full recovery from sedation occurred 36.3 mins. There is residual antinociception when assessed by ECT but not when assessed by noxious heat[1].

Molecular Weight

178.27

Formula

C₁₂H₁₈O

CAS No.

2078-54-8

SMILES

OC1=C(C(C)C)C=CC=C1C(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Keywords:

Propofol2,6-DiisopropylphenolGABA ReceptorEndogenous MetaboliteGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorglutamatereceptorexcitatorysynaptictransmissionantinociceptivesedationhypnoticInhibitorinhibitorinhibit

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Propofol
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HY-B0649
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