1. Cell Cycle/DNA Damage
    Epigenetics
  2. Sirtuin

SIRT5 inhibitor 

Cat. No.: HY-112634 Purity: 99.36%
Handling Instructions

SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.

For research use only. We do not sell to patients.

SIRT5 inhibitor Chemical Structure

SIRT5 inhibitor Chemical Structure

CAS No. : 2166487-21-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 817 In-stock
Estimated Time of Arrival: December 31
5 mg USD 550 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 4500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

View All Sirtuin Isoform Specific Products:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.

IC50 & Target

IC50: 0.11 μM (Sirtuin)[1].

In Vitro

SIRT5 inhibitor (compound 49) is a very potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM, >100-fold from compound 1[1].

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (185.24 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4819 mL 7.4095 mL 14.8190 mL
5 mM 0.2964 mL 1.4819 mL 2.9638 mL
10 mM 0.1482 mL 0.7409 mL 1.4819 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.08 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 2.08 mg/mL (3.08 mM); Clear solution; Need warming

  • 3.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.08 mM); Clear solution

References
Molecular Weight

674.81

Formula

C₃₁H₃₉FN₆O₆S₂

CAS No.

2166487-21-2

SMILES

O=S(N[[email protected]@H](CCCCNC(NCCC(O)=O)=S)C(N[[email protected]](C(NC1CCC1)=O)CC2=CNC3=CC=CC=C23)=O)(C4=CC(F)=CC=C4)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SIRT5 inhibitor
Cat. No.:
HY-112634
Quantity:

SIRT5 inhibitor

Cat. No.: HY-112634