1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. Lisinopril dihydrate

Lisinopril dihydrate (Synonyms: MK-521 dihydrate)

Cat. No.: HY-18206A Purity: >98.0%
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Lisinopri (dihydrate) (lMK-521 (dihydrate)) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. .

For research use only. We do not sell to patients.

Lisinopril dihydrate Chemical Structure

Lisinopril dihydrate Chemical Structure

CAS No. : 83915-83-7

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10 mM * 1 mL in Water USD 88 In-stock
Estimated Time of Arrival: December 31
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Estimated Time of Arrival: December 31
1 g USD 134 In-stock
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5 g USD 253 In-stock
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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Lisinopril dihydrate:

Top Publications Citing Use of Products

Publications Citing Use of MCE Lisinopril dihydrate

    Lisinopril dihydrate purchased from MCE. Usage Cited in: Hum Cell. 2020 Jan 18. 

    After 72 h of incubation, the protein expressions of collagen I, MMP9, α-SMA, smad2, smad3, p-smad2 and p-smad3 in control, TGF-β1 (5 ng/ml), MK-521 (10 μM), TGF-β1+MK-521, silibinin (40 μM) and TGF-β1+MK-521+silibinin are detected by Western blot. GAPDH was used as a loading control.
    • Biological Activity

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    • Customer Review


    Lisinopri (dihydrate) (lMK-521 (dihydrate)) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. .

    IC50 & Target


    In Vitro

    Lisinopri (dihydrate) (lMK-521 (dihydrate)) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Lisinopril may be used to treat hypertension and symptomatic congestive heart failure, to improve survival in certain individuals following myocardial infarction, and to prevent progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy[1][2].

    Clinical Trial
    Molecular Weight




    CAS No.



    O=C(O)[[email protected]]1N(C([[email protected]](CCCCN)N[[email protected]](C(O)=O)CCC2=CC=CC=C2)=O)CCC1.O.O


    Room temperature in continental US; may vary elsewhere.

    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    H2O : 20 mg/mL (45.30 mM; Need ultrasonic)

    DMSO : < 1 mg/mL (insoluble or slightly soluble)

    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.2649 mL 11.3245 mL 22.6490 mL
    5 mM 0.4530 mL 2.2649 mL 4.5298 mL
    10 mM 0.2265 mL 1.1325 mL 2.2649 mL
    *Please refer to the solubility information to select the appropriate solvent.
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    Lisinopril dihydrateMK-521 dihydrateAngiotensin-converting Enzyme (ACE)Inhibitorinhibitorinhibit

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