1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. Fosinopril sodium

Fosinopril sodium (Synonyms: SQ28555)

Cat. No.: HY-B0382 Purity: 98.48%
Handling Instructions

Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

For research use only. We do not sell to patients.

Fosinopril sodium Chemical Structure

Fosinopril sodium Chemical Structure

CAS No. : 88889-14-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1  mL in Water USD 139 In-stock
Estimated Time of Arrival: December 31
50 mg USD 126 In-stock
Estimated Time of Arrival: December 31
100 mg USD 168 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure. Target: ACE Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy [1-3].

Clinical Trial
Molecular Weight

585.64

Formula

C₃₀H₄₅NNaO₇P

CAS No.

88889-14-9

SMILES

O=C(O[Na])[[email protected]]1N(C(C[[email protected]@](CCCCC2=CC=CC=C2)(O[[email protected]](OC(CC)=O)C(C)C)=O)=O)C[[email protected]](C3CCCCC3)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (56.91 mM; Need ultrasonic)

DMSO : 1 mg/mL (1.71 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7075 mL 8.5377 mL 17.0753 mL
5 mM 0.3415 mL 1.7075 mL 3.4151 mL
10 mM 0.1708 mL 0.8538 mL 1.7075 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

FosinoprilSQ28555SQ 28555SQ-28555Angiotensin-converting Enzyme (ACE)Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Fosinopril sodium
Cat. No.:
HY-B0382
Quantity:
MCE Japan Authorized Agent: