TL1A
TL1A (TNF-like ligand 1A, TNFSF15, also VEGI) is a TNF family cytokine expressed predominantly by endothelial cells, monocytes, macrophages, dendritic cells and activated T cells, upregulated by inflammatory stimuli. TL1A exists as both a membrane-bound type II protein and a soluble homotrimer, and binds its functional receptor DR3 (TNFRSF25) with high affinity while also engaging the decoy receptor DcR3. Through DR3, TL1A provides co-stimulatory signals that selectively expand effector T cells, Th1, Th17 and Th9 populations, enhance cytokine production and promote T-cell survival; it simultaneously boosts group 2 and 3 innate lymphoid cell responses. TL1A is a central amplifier of mucosal inflammation: it is strongly associated with inflammatory bowel disease (both Crohn's and ulcerative colitis), where genetic variants and increased TL1A levels correlate with disease risk and severity, and it also drives rheumatoid arthritis, psoriasis and asthmatic inflammation. Anti-TL1A antibodies such as PF-06480605 and anti-DR3 strategies have entered clinical trials for IBD and autoimmune disease.
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TL1A Recombinant Proteins (20)
TL1A/TNFSF15 Trimer Protein, Human (HEK293, His-Flag)
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Cat. No.: HY-P78447
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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Animal-Free TL1A/TNFSF15 Protein, Human (His)
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Cat. No.: HY-P700153AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Human
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Cat. No.: HY-P71913
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque (HEK293, His)
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Cat. No.: HY-P701047
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Human (180a.a, HEK293, His)
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Cat. No.: HY-P701048
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Mouse (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P701046
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P77939
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC129935; Tumor Necrosis Factor (Ligand) Superfamily, Member 15; Tumor Necrosis Factor Superfamily Member 15; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor Ligand 1B; VEGI192A; TNLG1B
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TL1A/TNFSF15 Protein, Mouse (HEK293, His-Avi)
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Cat. No.: HY-P700839
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Rat (HEK293, Fc)
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Cat. No.: HY-P74508
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Mouse
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Cat. No.: HY-P72446
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Human (Biotinylated, HEK293, Avi-His)
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Cat. No.: HY-P702569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC129935; Tumor Necrosis Factor (Ligand) Superfamily, Member 15; Tumor Necrosis Factor Superfamily Member 15; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor Ligand 1B; VEGI192A; TNLG1B
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TL1A/TNFSF15 Protein, Human (161a.a, HEK293, His)
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Cat. No.: HY-P78447A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Human (168a.a, HEK293, Fc)
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Cat. No.: HY-P704407
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Mouse (HEK293, His)
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Cat. No.: HY-P704925
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Human (Biotinylated, HEK293, Avi-His, solution)
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Cat. No.: HY-P702569A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC129935; Tumor Necrosis Factor (Ligand) Superfamily, Member 15; Tumor Necrosis Factor Superfamily Member 15; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor Ligand 1B; VEGI192A; TNLG1B
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TL1A/TNFSF15 Protein, Human (O95150-2, HEK293, His)
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Cat. No.: HY-P71981
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Rat (HEK293, His)
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Cat. No.: HY-P704926
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Human (O95150-3, HEK293, His)
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Cat. No.: HY-P704406
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P705963
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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TL1A/TNFSF15 Protein, Rhesus Macaque (HEK293, His)
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Cat. No.: HY-P705986
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF15; TL1A; TNF Superfamily Member 15; Vascular Endothelial Growth Inhibitor-192A; Vascular Endothelial Cell Growth Inhibitor; Vascular Endothelial Growth Inhibitor; TNF Ligand-Related Molecule 1; TNF Superfamily Ligand TL1A; VEGI; MGC129934; TL1; MGC1
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
