B-cell Activating Factor (BAFF)
B-cell activating factor (BAFF, also BLyS, TNFSF13B, CD257) is a TNF family cytokine essential for B-cell survival and maturation, produced by monocytes, macrophages, dendritic cells, neutrophils and stromal cells. BAFF exists as a membrane-bound type II transmembrane protein that is cleaved by furin into a soluble trimer, and can assemble into 60-mer viral-like clusters that greatly enhance its potency. It binds three receptors: BAFF-R (specific to mature B cells), TACI and BCMA; signaling through BAFF-R activates the non-canonical NF-κB pathway, delivering tonic survival signals and supporting the transitional B-cell checkpoint, germinal center maintenance and plasma-cell longevity. BAFF overexpression drives lupus-like autoimmunity, Sjögren's syndrome and rheumatoid arthritis, whereas excessive BAFF blockade reduces immunoglobulin levels. Belimumab, an anti-BAFF antibody, is approved for systemic lupus erythematosus; atacicept, which neutralizes BAFF and APRIL together, is in late development.
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B-cell Activating Factor (BAFF) Protéines Recombinantes (18)
BAFF/TNFSF13B Protein, Human (CHO)
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Cat. No.: HY-P7003
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Human (HEK293, His)
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Cat. No.: HY-P70428
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Trimer Protein, Human (HEK293, His-Flag)
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Cat. No.: HY-P78384
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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Animal-Free BAFF/TNFSF13B Protein, Human (His)
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Cat. No.: HY-P700017AF
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P70816
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Human (HEK293, Fc)
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Cat. No.: HY-P70730
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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Animal-Free BAFF/TNFSF13B Protein, Mouse (His)
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Cat. No.: HY-P700161AF
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Trimer Protein, Cynomolgus (HEK293, His-Avi)
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Cat. No.: HY-P77571
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Cynomolgus (Biotinylated, HEK293, His-Flag-Avi)
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Cat. No.: HY-P77572
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Canine (HEK293, Fc)
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Cat. No.: HY-P75589
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Mouse (HEK293)
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Cat. No.: HY-P704315
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag)
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Cat. No.: HY-P78385
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis Factor Superfamily Member 13b; B-Cell-Activating Factor; Tumor Necrosis Factor-Like Protein ZTNF4; B-Lymphocyte Stimulator; ApoL Related Ligand TALL-1; THANK; B Lymphocyte Stimulator; CD257; CD257 Antigen; Tumor Necrosis Factor (Ligand) Superfamily, Member 13b; Delta4 BAFF; Tumor Necrosis Factor Ligand Superfamily Member 13B; Delta BAFF; TNF And ApoL-Related Leukocyte Expressed Ligand 1; TNLG7A; Epididymis Secretory Sperm Binding Protein; BLyS; TNF Superfamily Member 13b; TNF Homolog That Activates Apoptosis
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BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi)
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Cat. No.: HY-P700459
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Human (His-SUMO)
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Cat. No.: HY-P700531
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Rhesus Macaque (HEK293, Fc)
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Cat. No.: HY-P72442
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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BAFF/TNFSF13B Protein, Mouse (Biotinylated, HEK293, Avi-Fc)
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Cat. No.: HY-P705167
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis Factor Superfamily Member 13b; B-Cell-Activating Factor; Tumor Necrosis Factor-Like Protein ZTNF4; B-Lymphocyte Stimulator; ApoL Related Ligand TALL-1; THANK; B Lymphocyte Stimulator; CD257; CD257 Antigen; Tumor Necrosis Factor (Ligand) Superfamily, Member 13b; Delta4 BAFF; Tumor Necrosis Factor Ligand Superfamily Member 13B; Delta BAFF; TNF And ApoL-Related Leukocyte Expressed Ligand 1; TNLG7A; Epididymis Secretory Sperm Binding Protein; BLyS; TNF Superfamily Member 13b; TNF Homolog That Activates Apoptosis
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BAFF/TNFSF13B Protein, Mouse (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P705246
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis Factor Superfamily Member 13b; B-Cell-Activating Factor; Tumor Necrosis Factor-Like Protein ZTNF4; B-Lymphocyte Stimulator; ApoL Related Ligand TALL-1; THANK; B Lymphocyte Stimulator; CD257; CD257 Antigen; Tumor Necrosis Factor (Ligand) Superfamily, Member 13b; Delta4 BAFF; Tumor Necrosis Factor Ligand Superfamily Member 13B; Delta BAFF; TNF And ApoL-Related Leukocyte Expressed Ligand 1; TNLG7A; Epididymis Secretory Sperm Binding Protein; BLyS; TNF Superfamily Member 13b; TNF Homolog That Activates Apoptosis
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BAFF/TNFSF13B Trimer Protein, Human (Biotinylated, 152a.a, HEK293, His-Avi)
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Cat. No.: HY-P705471
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFSF13B; Dendritic Cell-Derived TNF-Like Molecule; Prev. TNFSF20; Tumor Necrosis Factor Ligand 7A; TALL-1; ZTNF4; TALL1; Tumor Necrosis Factor (Ligand) Superfamily, Member 20; BAFF; TNF- And APOL-Related Leukocyte Expressed Ligand 1; BLYS; Tumor Necrosis
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
