BAFF/TNFSF13B Protein, Cynomolgus (HEK293, His-Avi)

BAFF/TNFSF13B protein is a member of the TNF family and regulates immune responses and cell survival. It is also known as B cell activating factor, which plays a vital role in the development, activation and survival of B cells by binding to receptors such as BAFF-R. BAFF/TNFSF13B Protein, Cynomolgus (HEK293, His-Avi) is the recombinant cynomolgus-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of BAFF/TNFSF13B Protein, Cynomolgus (HEK293, His-Avi) is 145 a.a., with molecular weight of 55-60 kDa.

The BAFF/TNFSF13B protein belongs to the tumor necrosis factor (TNF) family, a group of cytokines involved in regulating immune responses and cell survival. BAFF/TNFSF13B, also known as B-cell activating factor, plays a crucial role in B-cell development, activation, and survival. It binds to its receptors, including BAFF receptor (BAFF-R), and promotes B-cell proliferation, antibody production, and the maintenance of mature B cells. BAFF/TNFSF13B is particularly important in the development and function of the immune system, as it helps to regulate B-cell homeostasis and immune tolerance. Dysregulation of BAFF/TNFSF13B signaling has been implicated in various autoimmune diseases and B-cell malignancies. Understanding the role of BAFF/TNFSF13B in normal physiology and disease pathology can provide valuable insights into potential therapeutic approaches for conditions involving B-cell dysfunction or dysregulation.

Cynomolgus

HEK293

N-His;N-Avi

A0A2K5V2X4 (T141-L285)

102123214  [NCBI]

55-60 kDa

Greater than 95% as determined by Tris-Bis PAGE

<1 EU/μg, determined by LAL method.