Imidazole-15N2
Based on 1 Customer Validation
Imidazole-15N2 (Glyoxaline-15N2) is 15N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CLPro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease.
For research use only. We do not sell to patients.
- Purity: 98.56%
- CAS No.: 74362-46-2
- Formula: C3H415N2
- Molecular Weight:70.06
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 74362-46-2
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Unlabeled Cas 288-32-4
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Appearance Solid
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Molecular Weight 70.06
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Formula C3H415N2
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Color White to off-white
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SMILES
C1=C[15N]=C[15NH]1
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Synonyms
Glyoxaline-15N2; 1,3-Diaza-2,4-cyclopentadiene-15N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[3]. Moncada S, et al. Imidazole: a selective inhibitor of thromboxane synthetase[J]. Prostaglandins. 1977 Apr;13(4):611-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)