9,10-Anthracenediyl-bis(methylene)dimalonic acid
Based on 4 publication(s) in Google Scholar
9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a biological dye and indicator used to detect singlet oxygen generation (SOG). 9,10-Anthracenediyl-bis(methylene)dimalonic acid is water-soluble derivative of anthracene. 9,10-Anthracenediyl-bis(methylene)dimalonic acid can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease of absorbance at 400 nm.
For research use only. We do not sell to patients.
- Purity : 98.00%
- CAS No.: 307554-62-7
- Formula: C22H18O8
- Molecular Weight:410.37
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) 9,10-Anthracenediyl-bis(methylene)dimalonic acid
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Customer Validation & Images
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Biological Activity
Description
In Vitro
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
1. Preparation of ABMDMA Staining Working Solution:[1]
ABMDMA in water was mixed with Pc4SNP or Pc4 to give a final concentration of 2 μM.
2. Detection of singlet oxygen generation:
2.1 In a typical procedure, 0.5 mL of ABMDMA water solution (0.07 mg/mL) was added to methylene blue (MB)-GO or MB water solutions both containing (MB/H2O) to give the final ABMDMA concentration of 3.33 μg/mL.
2.2 Next, 1 mL of MB-GO/ABMDMA or MB/ABMDMA solutions were poured into open quartz cuvettes and irradiated with a 785 nm laser for 55 min. The reactions were monitored with UV-vis spectroscopy by recording an absorbance decrease at 400 nm (λmax) at 5-min intervals.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Emission (Em)
407
Excitation (Ex)
380
Chemical Information
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CAS No. 307554-62-7
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Appearance Solid
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Molecular Weight 410.37
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Formula C22H18O8
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Color Light yellow to yellow
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SMILES
OC(C(C(O)=O)CC1=C(C=CC=C2)C2=C(CC(C(O)=O)C(O)=O)C3=C1C=CC=C3)=O
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Synonyms
ABMDMA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (4)
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Journal Impact Factor
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Most Recent
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Int J Nanomedicine
Magnetic Microbubbles Combined with ICG-Loaded Liposomes for Synergistic Mild-Photothermal and Ferroptosis-Enhanced Photodynamic Therapy of Melanoma. [Abstract]2025 Mar 10:20:2901-2921. PMID: 40093542
9,10-Anthracenediyl-bis(methylene)dimalonic acid purchased from MedChemExpress. Usage Cited in: Int J Nanomedicine. 2025 Mar 10:20:2901-2921. [Abstract]
The spectrum of ABDA (2 mM) absorbance treated with pure laser irradiation for different times in the absence of ICG-Lips.
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Front Chem
Cur@ZIF-8@BA nanomaterials with pH-responsive and photodynamic therapy properties promotes antimicrobial activity. [Abstract]2024 Jun 24:12:1417715. PMID: 38979404
9,10-Anthracenediyl-bis(methylene)dimalonic acid purchased from MedChemExpress. Usage Cited in: Front Chem. 2024 Jun 24:12:1417715. [Abstract]
Photodegradation of ABDA with Cur@ZIF-8@BA. The measurements were carried out under white light irradiation in PBS buffer.
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Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (243.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4368 mL | 12.1841 mL | 24.3683 mL | 60.9206 mL |
| 5 mM | 0.4874 mL | 2.4368 mL | 4.8737 mL | 12.1841 mL | |
| 10 mM | 0.2437 mL | 1.2184 mL | 2.4368 mL | 6.0921 mL | |
| 15 mM | 0.1625 mL | 0.8123 mL | 1.6246 mL | 4.0614 mL | |
| 20 mM | 0.1218 mL | 0.6092 mL | 1.2184 mL | 3.0460 mL | |
| 25 mM | 0.0975 mL | 0.4874 mL | 0.9747 mL | 2.4368 mL | |
| 30 mM | 0.0812 mL | 0.4061 mL | 0.8123 mL | 2.0307 mL | |
| 40 mM | 0.0609 mL | 0.3046 mL | 0.6092 mL | 1.5230 mL | |
| 50 mM | 0.0487 mL | 0.2437 mL | 0.4874 mL | 1.2184 mL | |
| 60 mM | 0.0406 mL | 0.2031 mL | 0.4061 mL | 1.0153 mL | |
| 80 mM | 0.0305 mL | 0.1523 mL | 0.3046 mL | 0.7615 mL | |
| 100 mM | 0.0244 mL | 0.1218 mL | 0.2437 mL | 0.6092 mL |
9,10-Anthracenediyl-bis(methylene)dimalonic acid Related Classifications
HY-D0034 Related Classifications
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