1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

4,6-Dioxoheptanoic acid 

Cat. No.: HY-W010184 Purity: >97.0%
Handling Instructions

4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

For research use only. We do not sell to patients.

4,6-Dioxoheptanoic acid Chemical Structure

4,6-Dioxoheptanoic acid Chemical Structure

CAS No. : 51568-18-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg USD 110 In-stock
Estimated Time of Arrival: December 31
100 mg USD 180 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.3231 mL 31.6156 mL 63.2311 mL
5 mM 1.2646 mL 6.3231 mL 12.6462 mL
10 mM 0.6323 mL 3.1616 mL 6.3231 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

158.15

Formula

C₇H₁₀O₄

CAS No.

51568-18-4

SMILES

CC(=O)CC(=O)CCC(O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
4,6-Dioxoheptanoic acid
Cat. No.:
HY-W010184
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4,6-Dioxoheptanoic acid

Cat. No.: HY-W010184