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N-Methylprotoporphyrin IX is a potent inhibitor of ferrochelatase enzyme.

For research use only. We do not sell to patients.

N-Methylprotoporphyrin IX Chemical Structure

N-Methylprotoporphyrin IX Chemical Structure

CAS No. : 79236-56-9

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Based on 1 publication(s) in Google Scholar

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Description

N-Methylprotoporphyrin IX is a potent inhibitor of ferrochelatase enzyme[1].

IC50 & Target

ferrochelatase enzyme[1]

Molecular Weight

576.68

Formula

C35H36N4O4

CAS No.
Appearance

Solid

Color

Brown to black

SMILES

O=C(O)CCC1=C2/C=C3C(CCC(O)=O)=C(C)C(/C=C(N/4C)/C(C)=C(C=C)C4=C\C5=N/C(C(C=C)=C5C)=C\C(N2)=C1C)=N/3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 15 mg/mL (26.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7341 mL 8.6703 mL 17.3406 mL
5 mM 0.3468 mL 1.7341 mL 3.4681 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7341 mL 8.6703 mL 17.3406 mL 43.3516 mL
5 mM 0.3468 mL 1.7341 mL 3.4681 mL 8.6703 mL
10 mM 0.1734 mL 0.8670 mL 1.7341 mL 4.3352 mL
15 mM 0.1156 mL 0.5780 mL 1.1560 mL 2.8901 mL
20 mM 0.0867 mL 0.4335 mL 0.8670 mL 2.1676 mL
25 mM 0.0694 mL 0.3468 mL 0.6936 mL 1.7341 mL
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N-Methylprotoporphyrin IX Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N-Methylprotoporphyrin IX
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HY-129430
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