Tetraphenylporphyrin  (Synonyms: TPP; Tetraphenylporphine; meso-Tetraphenylporphyrin)

Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research^[1].

Porphyrins are dyes and cofactors found in hemoglobin and cytochromes and are related to chlorophyll and vitamin B12.
The research of natural porphyrins is complicated by their low symmetry and the presence of polar substituents. Tetraphenylporphyrin is symmetrically substituted and easily synthesized compared to natural porphyrins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

614.74

C₄₄H₃₀N₄

917-23-7

Solid

Purple to black

C1(/C2=CC=CC=C2)=C3C=CC(/C(C4=CC=CC=C4)=C5C=C/C(N/5)=C(C6=CC=CC=C6)/C(C=C/7)=NC7=C(C8=CC=CC=C8)/C9=CC=C1N9)=N/3

Room temperature in continental US; may vary elsewhere.

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Benoît Chauvin, et al. Diprotonation process of meso-tetraphenylporphyrin derivatives designed for photodynamic therapy of cancers: from multivariate curve resolution to predictive QSPR modeling. Anal Chim Acta. 2011 Oct 31;705(1-2):306-14.  [Content Brief]