Lumogallion
Based on 1 publication(s) in Google Scholar
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 4386-25-8
- Formula: C12H9ClN2O6S
- Molecular Weight:344.73
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Lumogallion
More
Biological Activity
Lumogallion (1 mM, 45 min) can be used to detect aluminum levels in brain tissue of Alzheimer's patients[1].
Lumogallion can be used as a probe to stain live cells with intracellular aluminum adjuvant[2].
Lumogallion (10 μM, 60 min) can be used to detect aluminum content in root tip cell tissue of plants[3].
Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
1. Dissolved Lumogallion in 0.1 M acetate buffer (pH 5.2).
2. Sample and 10 μM Lumogallion were co-incubated for 60 min in the dark.
3. Washed the mixed sample well with acetate buffer solution twice, 15 minutes each, and observed under a confocal laser microscope.
4. Excitation wavelength is 488 nm , emission wavelength is 520 nm.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
580
490
Chemical Information
-
CAS No. 4386-25-8
-
Appearance Solid
-
Molecular Weight 344.73
-
Formula C12H9ClN2O6S
-
Color Brown to reddish brown
-
SMILES
O=S(C1=CC(Cl)=CC(/N=N/C2=CC=C(O)C=C2O)=C1O)(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
J Hazard Mater
Mechanistic insight into airborne particulate matter PM10 as an environmental hazard for hemorrhagic stroke: Evidence from in vitro and in vivo studies. [Abstract]2024 Oct 28:480:136319. PMID: 39488980
Solvent & Solubility
DMSO : 100 mg/mL (290.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
[1]. Ambreen Mirza, et al. The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy. J Alzheimers Dis. 2016 Oct 18;54(4):1333-1338. [Content Brief]
[2]. Irene Mile, et al. Al adjuvants can be tracked in viable cells by lumogallion staining. J Immunol Methods. 2015 Jul;422:87-94. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9008 mL | 14.5041 mL | 29.0082 mL | 72.5205 mL |
| 5 mM | 0.5802 mL | 2.9008 mL | 5.8016 mL | 14.5041 mL | |
| 10 mM | 0.2901 mL | 1.4504 mL | 2.9008 mL | 7.2521 mL | |
| 15 mM | 0.1934 mL | 0.9669 mL | 1.9339 mL | 4.8347 mL | |
| 20 mM | 0.1450 mL | 0.7252 mL | 1.4504 mL | 3.6260 mL | |
| 25 mM | 0.1160 mL | 0.5802 mL | 1.1603 mL | 2.9008 mL | |
| 30 mM | 0.0967 mL | 0.4835 mL | 0.9669 mL | 2.4174 mL | |
| 40 mM | 0.0725 mL | 0.3626 mL | 0.7252 mL | 1.8130 mL | |
| 50 mM | 0.0580 mL | 0.2901 mL | 0.5802 mL | 1.4504 mL | |
| 60 mM | 0.0483 mL | 0.2417 mL | 0.4835 mL | 1.2087 mL | |
| 80 mM | 0.0363 mL | 0.1813 mL | 0.3626 mL | 0.9065 mL | |
| 100 mM | 0.0290 mL | 0.1450 mL | 0.2901 mL | 0.7252 mL |
Lumogallion Related Classifications
HY-137296 Related Classifications
Powered by Bioz