meso-Tetra(4-pyridyl)porphine

Cat. No.: HY-W008874 Pureza: ≥95.0%: Ficha de datos
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meso-Tetra(4-pyridyl)porphine (Compound 10) is a porphyrin derivative. meso-Tetra(4-pyridyl)porphine is a weak inhibitor of human topoisomerase I (Top1) with an EC₅₀ value greater than 50 µM. meso-Tetra(4-pyridyl)porphine can be used in tumor research.

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meso-Tetra(4-pyridyl)porphine Estructura química

No. CAS : 16834-13-2

Tamaño	Stock	Cantidad
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
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50 g	Obtener un presupuesto

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Topoisomerase Topo I Topo II DNA gyrase

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Descripciòn	meso-Tetra(4-pyridyl)porphine (Compound 10) is a porphyrin derivative. meso-Tetra(4-pyridyl)porphine is a weak inhibitor of human topoisomerase I (Top1) with an EC₅₀ value greater than 50 µM. meso-Tetra(4-pyridyl)porphine can be used in tumor research^[1].
Peso molecular	618.70
Fòrmula	C₄₀H₂₆N₈
No. CAS	16834-13-2
Appearance	Solid
Color	Purple to black
SMILES	C1(/C2=CC=NC=C2)=C3C=CC(/C(C4=CC=NC=C4)=C5C=C/C(N/5)=C(C6=CC=NC=C6)/C(C=C/7)=NC7=C(C8=CC=NC=C8)/C9=CC=C1N9)=N/3
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Pureza y Documentación	Purity: ≥97.0% Select Batch: Ficha de datos (282 KB) SDS (396 KB) COA (270 KB) HNMR (116 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Das SK, et al. Neutral Porphyrin Derivative Exerts Anticancer Activity by Targeting Cellular Topoisomerase I (Top1) and Promotes Apoptotic Cell Death without Stabilizing Top1-DNA Cleavage Complexes. J Med Chem. 2018 Feb 8;61(3):804-817. [Content Brief]