59-67-6
59-67-6
Chemical Structure
Niacin
Synonym(s): Nicotinic acid; Vitamin B3
- CAS No.: 59-67-6
- Formula:C6H5NO2
- Molecular Weight:123.11
IUPAC Name: nicotinic acid
InChIKey: PVNIIMVLHYAWGP-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN=C1)O
Biological Activity: Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Niacin | 99.96% | Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases. | ||||||||||||||||||||
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Niacin (standard) | 99.98% | Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases. | ||||||||||||||||||||
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Niacin-13C6 | 99.90% | Niacin-13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group. | ||||||||||||||||||||
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Niacin-15N,13C3 | Niacin-15N,13C3 is the 13C and 15N labeled Niacin. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases. | |||||||||||||||||||||
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Niacin-d4 | 99.61% | Niacin-d4 (Nicotinic acid-d4) is the deuterium labeled Niacin (HY-B0143). Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group. | ||||||||||||||||||||
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N-Methylnicotinamide-d4 | 98.18% | N-Methylnicotinamide-d4 is the deuterium labeled N-Methylnicotinamide (HY-124124). N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. | ||||||||||||||||||||
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Niacin hydrochloride | 99.36% | Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases. | ||||||||||||||||||||
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Nicotinamide (GMP) | Nicotinamide (GMP) (Niacinamide (GMP)) is the GMP level of Nicotinamide (HY-B0150). GMP guidelines are used to produce Nicotinamide (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity. | |||||||||||||||||||||
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Nicotinamide-d4 | 99.94% | Nicotinamide-d4 is the deuterium labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. | ||||||||||||||||||||
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Nicotinamide-15N,13C3 | Nicotinamide-15N,13C3 is the 13C-labeled and 15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. | |||||||||||||||||||||
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Nicotinamide-13C6 | 99.90% | Nicotinamide-13C6 is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1. | ||||||||||||||||||||
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Isoniazid-d4 | 99.86% | Isoniazid-d4 is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity. | ||||||||||||||||||||
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Methyl nicotinate-d4 | 99.5% | Methyl nicotinate-d4 is the deuterium labeled Methyl nicotinate. Methyl nicotinate, the methyl ester of Niacin found in alcoholic beverages, that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. | ||||||||||||||||||||
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Picolinic acid | 99.98% | Picolinic acid (PCL 016) is a topical antiviral agent, which inhibits adenovirus replication in rabbits. | ||||||||||||||||||||
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Isonicotinic acid | 99.96% | Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses. | ||||||||||||||||||||
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Isonicotinic acid-d4 | 98.12% | Isonicotinic acid-d4 is the deuterium labeled Isonicotinic acid (HY-I0736). Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses. | ||||||||||||||||||||
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Benzoic acid-d5 | 98.98% | Benzoic acid-d5 is a deuterium substitute for Benzoic acid. Benzoic acid is an aromatic alcohol that occurs naturally in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid can act as a preservative by inhibiting bacteria and fungi. | ||||||||||||||||||||
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Pyridazine-4-carboxylic acid | 99.64% | Pyridazine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Isonicotinamide-d4 | 99.91% | Isonicotinamide-d4 is the deuterium labeled Isonicotinamide. | ||||||||||||||||||||
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3-Pyridine-2,4,5,6-d4 -carboxylic acid, ethyl ester | 3-Pyridine-2,4,5,6-d4 -carboxylic acid, ethyl ester is the deuterium labeled 3-Pyridine-2,4,5,6-carboxylic acid, ethyl ester. | |||||||||||||||||||||
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Picolinic acid-d4 | 99.99% | Ppicolinic-3,4,5,6-d4 acid is the deuterium labeled Ppicolinic acid. | ||||||||||||||||||||
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Nicotinamide-15N | 99.65% | Nicotinamide-15N (Niacinamide-15N) is the deuterium labeled Nicotinamide (HY-B0150). Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity. | ||||||||||||||||||||
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3-Pyridinecarboxaldehyde-d4 | 3-Pyridinecarboxaldehyde-d4 is the deuterium labeled 3-Pyridinecarboxaldehyde. | |||||||||||||||||||||
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References
- [1]. Areeg M Almubarak, et al. Supplementation with Niacin during in vitro maturation improves the quality of porcine embryos. Theriogenology. 2021 Jul 15;169:36-46. doi: 10.1016/j.theriogenology.2021.04.005. Epub 2021 Apr 18. [Content Brief]
- [2]. Nobuhiro Hirakawa, et al. Anti-invasive activity of niacin and trigonelline against cancer cells. Biosci Biotechnol Biochem. 2005 Mar;69(3):653-8. [Content Brief]
