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Niacin hydrochloride

(Synonyms: Nicotinic acid hydrochloride; Vitamin B3 hydrochloride)
12 Cited Publications
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Based on 12 publication(s) in Google Scholar

Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases.

For research use only. We do not sell to patients.

  • CAS No.: 636-79-3
  • Formula: C6H6ClNO2
  • Molecular Weight:159.57
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Niacin hydrochloride Chemical Structure
    Niacin hydrochloride Chemical Structure
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
CAS No.: 636-79-3
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  • Niacin hydrochloride Chemical Structure
    Niacin hydrochloride Chemical Structure
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    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Oct 18;26(20):10132. [Abstract]

    Customer Validation
     Seven-week-old male C57BL/6 mice were shaved and treated topically with vehicle, 3% rebamipide, 0.5% niacin (NA, lipolysis inhibitor), 0.05% rosiglitazone (RSG, PPARγ agonist), or combination therapies for 26 days (n = 6 for each group). Photographs were taken on day 26 post-treatment. H&E staining of skin sections revealed hair follicle morphology. Ki67 immunofluorescent staining showed that rebamipide-induced hair regeneration was inhibited by NA and RSG.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Commun Biol. 2023 Mar 2;6(1):235. [Abstract]

    Customer Validation
     Niacin (400 mg/kg/day). Body weight of mice during the experiment after supplementation with the MCD diet decreased gradually.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Mil Med Res. 2022 Aug 23;9(1):46. [Abstract]

    Customer Validation
     BMDMs (LPS-primed) were treated with propionate (C3, 3 mmol/L), butyrate (C4, 0.5 mmol/L), TSA (50 nmol/L), Panobinostat (25 nmol/L), AR42062 (25 μmol/L), 4-CMTB (100 μmol/L), and niacin (1 mmol/L; 6 h) and then stimulated with CoCrMo alloy particles.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2022 Mar 9;20(1):120. [Abstract]

    Customer Validation
     BMDMs (LPS-primed) were treated with different doses of BHB, Niacin (100 μM; 6 h), TSA (50 nM), and LBH589 (25 nM) and stimulated with CoCrMo particles. Supernatants were collected for Caspase-1 and IL-1β detection by western blot.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2022 Mar 9;20(1):120. [Abstract]

    Customer Validation
     BMDMs (LPS-primed) were treated with different doses of BHB, Niacin (100 μM; 6 h), TSA (50 nM), and LBH589 (25 nM) and stimulated with CoCrMo particles. IL-1β was analyzed by ELISA in the supernatants.

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    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Glia. 2018 Feb;66(2):256-278. [Abstract]

    Customer Validation
     Representative images and quantitative analysis showing the effects of Niacin (1 mM, 10 min) and MK-6892 (10 lM, 10 min) on Akt phosphorylation levels in primary cultured microglia.

  • Niacin hydrochloride