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Niacin hydrochloride

(Synonyms: Nicotinic acid hydrochloride; Vitamin B3 hydrochloride)
12 Cited Publications
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Based on 12 publication(s) in Google Scholar

Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases.

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  • CAS No.: 636-79-3
  • Formule: C6H6ClNO2
  • Masse moléculaire:159.57
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Niacin hydrochloride Chemical Structure
    Niacin hydrochloride Chemical Structure
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
  • Experimental Validation Results for Niacin hydrochloride
CAS No.: 636-79-3
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  • Niacin hydrochloride Chemical Structure
    Niacin hydrochloride Chemical Structure
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    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Oct 18;26(20):10132. [Abstract]

    Customer Validation
     Seven-week-old male C57BL/6 mice were shaved and treated topically with vehicle, 3% rebamipide, 0.5% niacin (NA, lipolysis inhibitor), 0.05% rosiglitazone (RSG, PPARγ agonist), or combination therapies for 26 days (n = 6 for each group). Photographs were taken on day 26 post-treatment. H&E staining of skin sections revealed hair follicle morphology. Ki67 immunofluorescent staining showed that rebamipide-induced hair regeneration was inhibited by NA and RSG.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Commun Biol. 2023 Mar 2;6(1):235. [Abstract]

    Customer Validation
     Niacin (400 mg/kg/day). Body weight of mice during the experiment after supplementation with the MCD diet decreased gradually.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Mil Med Res. 2022 Aug 23;9(1):46. [Abstract]

    Customer Validation
     BMDMs (LPS-primed) were treated with propionate (C3, 3 mmol/L), butyrate (C4, 0.5 mmol/L), TSA (50 nmol/L), Panobinostat (25 nmol/L), AR42062 (25 μmol/L), 4-CMTB (100 μmol/L), and niacin (1 mmol/L; 6 h) and then stimulated with CoCrMo alloy particles.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2022 Mar 9;20(1):120. [Abstract]

    Customer Validation
     BMDMs (LPS-primed) were treated with different doses of BHB, Niacin (100 μM; 6 h), TSA (50 nM), and LBH589 (25 nM) and stimulated with CoCrMo particles. Supernatants were collected for Caspase-1 and IL-1β detection by western blot.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2022 Mar 9;20(1):120. [Abstract]

    Customer Validation
     BMDMs (LPS-primed) were treated with different doses of BHB, Niacin (100 μM; 6 h), TSA (50 nM), and LBH589 (25 nM) and stimulated with CoCrMo particles. IL-1β was analyzed by ELISA in the supernatants.

  • 1/16

    Niacin hydrochloride purchased from MedChemExpress. Usage Cited in: Glia. 2018 Feb;66(2):256-278. [Abstract]

    Customer Validation
     Representative images and quantitative analysis showing the effects of Niacin (1 mM, 10 min) and MK-6892 (10 lM, 10 min) on Akt phosphorylation levels in primary cultured microglia.

  • Niacin hydrochloride