Copy Link Print Information

Dihydromyricetin

(Synonyms: Ampelopsin; Ampeloptin)
26 Cited Publications
Customer Review

Based on 26 publication(s) in Google Scholar

Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM.

For research use only. We do not sell to patients.

  • Purity: 99.73%
  • CAS No.: 27200-12-0
  • Formula: C15H12O8
  • Molecular Weight:320.25
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Dihydromyricetin Chemical Structure
    Dihydromyricetin Chemical Structure
  • Experimental Validation Results for Dihydromyricetin
  • Experimental Validation Results for Dihydromyricetin
  • Experimental Validation Results for Dihydromyricetin
  • Experimental Validation Results for Dihydromyricetin
  • Experimental Validation Results for Dihydromyricetin
CAS No.: 27200-12-0
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Dihydromyricetin:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Solvent & Solubility
  • Protocol
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Dihydromyricetin

More
Customer Validation & Images
Histological Imaging/StainingWBIFRT-PCR
  • Histological Imaging/Staining
  • WB
  • IF
  • RT-PCR
  • WB

All mTOR Isoforms

More

All DNA/RNA Synthesis Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Dihydromyricetin Chemical Structure
    Dihydromyricetin Chemical Structure
    1/16
  • 1/16

    Dihydromyricetin purchased from MedChemExpress. Usage Cited in: Mol Ther. 2019 May 8;27(5):1051-1065. [Abstract]

    Customer Validation
     DHM (500 mg/kg/day) was suspended in 0.9% saline and intragastrically administered to C57BL/6J mice 7 days before UUO surgery and continued until the end of the experiment. Representative micrographs of H&E and Masson trichrome staining of mouse kidney sections at 14 days after UUO surgery were shown.

  • 1/16

    Dihydromyricetin purchased from MedChemExpress. Usage Cited in: Mol Ther. 2019 May 8;27(5):1051-1065. [Abstract]

    Customer Validation
     DHM (500 mg/kg/day) was suspended in 0.9% saline and intragastrically administered to C57BL/6J mice 7 days before UUO surgery and continued until the end of the experiment. Western blotting analysis was performed to assess E-cadherin, $\alpha$-SMA, and fibronectin protein levels in UUO mice at 14 days after surgery.

  • 1/16

    Dihydromyricetin purchased from MedChemExpress. Usage Cited in: Mol Ther. 2019 May 8;27(5):1051-1065. [Abstract]

    Customer Validation
     Representative immunostaining of E-cadherin, $\alpha$-SMA, and fibronectin in the obstructed kidneys at 14 days after UUO surgery. E-cadherin (green), fibronectin (red), and DAPI (blue) were shown. The scale bars corresponded to 50 μm. DHM (500 mg/kg/day) was suspended in 0.9% saline and intragastrically administered to C57BL/6J mice 7 days before UUO surgery and continued until the end of the experiment.

  • 1/16

    Dihydromyricetin purchased from MedChemExpress. Usage Cited in: Mol Ther. 2019 May 8;27(5):1051-1065. [Abstract]

    Customer Validation
     qRT-PCR analysis of miR-34a expression in HK-2 cells pretreated with different concentrations of DHM for 24 h followed by incubation with 10 ng/mL TGF-β1 for 24 or 48 h.

  • 1/16

    Dihydromyricetin purchased from MedChemExpress. Usage Cited in: Mol Ther. 2019 May 8;27(5):1051-1065. [Abstract]

    Customer Validation
     Western blotting analysis of Klotho in HK-2 cells pretreated with DHM (100 mM) for 24 h followed by incubation with 10 ng/mL TGF-β1 for 48 h.

  • Dihydromyricetin